Syntheses and Configuration Inversion of Substituted Oxazolines

The present paper covers the simply and highly stereoselective syntheses of (α-S, 4S)-2-dichloromethyl-4, 5-dihydro-α-(4-nitrophenyl)-4-oxazolemethanol (4a), (α-S, 4S)-2-methyl-4, 5-dihydro-α-(4-nitrophenyl)-4-oxazolemethanol (4b), and (α-R, 4R)-2-dichloromethyl-4, 5-dihydro-α-[(4-methylsulfonyl)phenyl]-4-oxazolemethanol(4c) with good yields(80％—90％). A configuration inversion product, (1R, 2S)-2-dichloroacetamido-1-(4-nitrophenyl)-1, 3-propanediol (8), was obtained during our attempting to convert compound 4a into (4S, 5R)-2-(dichloromethyl)-4, 5-dihydro-5-(4-nitrophenyl)-4-oxazolemethanol(7).     

含3-甲基苯基-2,3-二氮杂萘-1-酮结构聚醚酰胺的合成、表征与性能

合成了一种新型芳香二胺双-(4-氨基苯基)-4-(3-甲基-4-苯氧基)-2,3-二氮杂萘-1-酮(1)[2-(4-aminophenyl)-4-(3-methyl-4-phenoxy)-2,3-phthalazinone-1,DAMPP].采用Yamazaki体系,二胺(1)能与多种芳香二酸进行溶液亲核缩聚反应,制得一类新型聚芳醚酰胺,其特性粘度为0.40～0.60dL/g;以MS,FTIR和¹HNMR等分析手段研究了新型二胺单体及其聚合物的结构;利用DSC和TGA研究了聚合物的耐热性能,结果表明,新型聚芳酰胺具有高的玻璃化转变温度为598～620K,N2气气氛中10%热质量损失温度在673K以上.聚合物2a～2c的表面电阻系数为3.75×10¹⁴～9.87×10¹⁵Ω,体积电阻系数为1.39×10¹⁶～4.09×10¹⁶Ω·cm.聚合物在二甲基甲酰胺、1-甲基吡咯烷酮和间甲酚等极性有机溶剂中可溶解,并经浇注得到透明、韧性薄膜.     

高张力笼形氮杂环化合物的合成

以六苄基六氮杂异伍兹烷(HBIW)为母体,Pd(OH)₂/C为催化剂,在温和条件下,通过选择性催化氢解脱苄,使部分或全部苄基被其它官能团(如CH₃O-,C₂H₅-,CHO-)取代,合成了4种N-取代六氮杂异伍兹烷,并鉴定了它们的结构.这些化合物都是高张力的笼形氮杂环化合物,且均可作为合成六硝基六氮杂异伍兹烷(HNIW)的前体,而HNIW是当今最引人注目和最有军用前景的高能量密度化合物(HEDC).     

邻溴苯基-2-(口恶)唑啉的合成研究

改进了邻溴苯基-2-(口恶)唑啉的合成方法,使得N-(β-羟乙基)-2-(口恶)溴苯甲酰胺在氯化亚砜作用下缩合成唑啉的收率从40%左右提高到84%,并避免了使用NaH试剂,为芳基-2-(口恶)唑啉的合成提供一条方便、经济的路线.实验结果表明,反应温度对唑啉的收率的影响显著,随着反应温度的升高收率明显降低,室温下几乎得不到目标产物.根据实验结果推测其反应过程是经过互变异构酰亚胺中间物Ⅰ进行的.     

MULTILAYER ORGANIC LEDS BASED ON A NEW DYE-DOPED POLYMER*

A blue dye, l-benzothiazoly-3-phenyl-pyrazoline (BTPP) was found to function as bright lightemitting dye in organic electroluminescent devices. This heterocyclic compound exhibits good characteristicsof blue photoluminescence and electroluminescence, which has emission peak at 445 nm.The thin films offluorescent dye dispersed in poly(N-vinylcarbazole) (PVK) could serve as light-emitting layers in multilayerorganic LEDs. 2-(4-Biphenyl)-5-(4-tert-butylpheynyl)-1,3,4-oxadiazole (PBD) and tris-(8-hydroxyquinoline)aluminum (Alq3) were introduced into double-layer and three-layer devices respectively. The introduction ofelectron transport material Alq_3 enhanced the electron injection and luminous efficiency, as compared withdouble-layer devices. Maximum brightness and luminous efficiency can be reached up to 190 cd/m~2 and0.31 m/W, respectively.     

Studies on Nucleosides(Ⅵ)-Stereoselective Synthesis of Triazoline-thione NuCleosides

A series of heterocyclic compounds of triazole thione substituted by tetrazole(I)were prepared using nicotinic acid as starting material through several steps.They reacted with 1-O-trifluoroacety1-2,3,5-O-tri-benxoyl-β-D-ribofuranose(Ⅱ) inanhydrous CH₂Cl₂ at room temperature in the presence of BF₃·Et₂O to give nine new nucleosides, named as 3-[5-(3-pyridyl)-tetrazol-2-yl-methylene]-4-aryl,2,4-triazole-5-(4H)-thione-2, 3, 5-O-tribenwyl-β-D-ribo-furanoside(Ⅲ)(Ar=C₆H₅,o-MeC₆H₄,m-MeC₆H₄,p-MeC₆H₄,o-MeC₆H₄,p-MeC₆H₄,p-EtOC₆H₃,3,4-Me₂C₆H₄,a-C₁₀H₇).The structures and compositions were characterized by means of elemental analysis and spectroscopic methods.