Intravascular 3.0 T MRI Using an Imaging-Guidewire: a Feasibility Study in Swine

This study was to validate the feasibility of using a magnetic resonance imaging-guidewire (MRIG) for intravascular 3.0 T MR imaging of deep-seated arterial walls of large animals. The functionality of a 0.032-in. MRIG was evaluated and the signal-to-noise ratio (SNR) was calculated. Then, MRI of ten iliofemoral arteries of six pigs was acquired by MRIG and surface coil. The difference in the SNRs of the arterial walls between different coils was compared. Histology examined the potential thermal injuries of the imaged vessels. The MRIG functioned with the 3.0 T MR scanner. The average SNR of the arterial walls was significantly higher with the MRIG than with the surface coils (76.22 ± 34.76 vs. 12.63 ± 4.25, P < 0.01). Histology showed no evidence of thermal injuries at the vessel walls. This study validated the feasibility of generating intravascular 3.0 T MRI of deep-seated arterial walls in large animals, which should facilitate the translation of this technique from 1.5 to 3.0 T MR scanner.     

Dissipative soliton resonance in a passively mode-locked fiber laser

The phenomenon of dissipative soliton resonance (DSR) predicts that an increase of pulse energy by orders of magnitude can be obtained in laser oscillators. Here, we prove that DSR is achievable in a realistic ring laser cavity using nonlinear polarization evolution as the mode-locking mechanism, whose nonlinear transmission function is adjusted through a set of waveplates and a passive polarizer. The governing model accounts explicitly for the arbitrary orientations of the waveplates and the polarizer, as well as the gain saturation in the amplifying medium. It is shown that DSR is achievable with realistic laser settings. Our findings provide an excellent design tool for optimizing the mode-locking performance and the enhancement of energy delivered per pulse by orders of magnitude.     

Picoradian deflection measurement with an interferometric quasi-autocollimator using weak value amplification

We present an "interferometric quasi-autocollimator" that employs weak value amplification to measure angular deflections of a target mirror. The device has been designed to be insensitive to all translations of the target. We present a conceptual explanation of the amplification effect used by the device. An implementation of the device demonstrates sensitivities better than 10 picoradians per root hertz between 10 and 200 Hz.     

Wear resistance of reactive plasma sprayed and laser remelted TiB2-TiC0.3N0.7 based composite coatings against medium carbon steel

Wear resistance of reactive plasma sprayed TiB₂-TiC_0.3N_0.7 based composite coatings and the as-sprayed coating with laser surface treatment was investigated using plate-on-plate tests. Wear tests were performed at different normal loads and sliding speeds under dry sliding conditions in air. The surface morphologies of counterparts against as-sprayed and laser remelted coatings were investigated. The microstructure and chemical composition of wear debris and coatings were studied using scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS), respectively. The results show that the wear resistance of the laser remelted coating is improved significantly due to their increased microhardness and reduced flaws. The primary wear mechanism of the remelted coating is oxidation wear and its minor wear mechanisms are grain abrasion and fatigue failure during the course of wear test. In contrast, the primary wear mechanism of the as-sprayed coating is grain abrasion at the low sliding speed (370 rpm) and fatigue failure at the high sliding speed (549 rpm). The oxidation wear mechanism is a minor contributor for the as-sprayed coating.     

Micromegas prototypes with thermo-bond film separators

In this paper we report the results of Micromegas prototypes constructed by attaching micromesh to an anode using thermo-bond films. The excellent metal attaching ability and good dielectical property of this kind of film make it a promising material to be used as avalanche gap spacers. Several prototypes are successfully made. The electron transmission properties are first studied and then the gas gain is measured in argon-isobutane mixtures. The maximum gain of more than 10⁴ is easily obtained. The energy resolutions for ⁵⁵Fe 5.9 keV K_α ray can be better than 20% over one magnitude in gain for different operational gas mixtures and the best energy resolution of 13.7% (FWHM) can be achieved with the gas mixture of 94% argon concentration. The preliminary test results of the prototypes with sensitive area of 45 mm×45 mm without internal support show good uniformity across the sensitive area.     

Evidence for shape coexistence at medium spin in Rb

Four previously known rotational bands in ⁷⁶Rb have been extended to moderate spins using the Gammasphere and Microball γ ray and charged particle detector arrays and the ⁴⁰Ca(⁴⁰Ca, 3pn) reaction at a beam energy of 165 MeV. The properties of two of the negative-parity bands can only readily be interpreted in terms of the highly successful Cranked Nilsson-Strutinsky model calculations if they have the same configuration in terms of the number of g9/2 particles, but they result from different nuclear shapes (one near-oblate and the other near-prolate). These data appear to constitute a unique example of shape coexisting structures at medium spins.     

Dynamics of dark-bright solitons in cigar-shaped Bose-Einstein condensates

We explore the stability and dynamics of dark-bright (DB) solitons in two-component elongated Bose-Einstein condensates by developing effective one-dimensional vector equations and solving the three-dimensional Gross-Pitaevskii equations. A strong dependence of the oscillation frequency and of the stability of the DB soliton on the atom number of its components is found; importantly, the wave may become dynamically unstable even in the 1D regime. As the atom number in the dark-soliton-supporting component is further increased, spontaneous symmetry breaking leads to oscillatory dynamics in the transverse degrees of freedom. Moreover, the interactions of two DB solitons are investigated with an emphasis on the importance of their relative phases. Experimental results showcasing multiple DB soliton oscillations and a DB-DB collision in a Bose-Einstein condensate consisting of two hyperfine states of ⁸⁷Rb confined in an elongated optical dipole trap are presented.     

4D localization in Randall-Sundrum 2 supergravity and in Vasiliev theories

We discuss the problem of localization of 4D massless states in Randall-Sundrum 2 (one-brane) models. A Randall-Sundrum 2 construction starting from N=8 gauged supergravity in 5D anti-de Sitter space gives rise to an N=4 supergravity-matter system. We explicitly show that only the modes of the N=4 graviton supermultiplet localize on the 4D brane, streamlining and generalizing previous works. We also point out that while charged 1/4 BPS black holes do exist in the 4D theory, they are always produced in sets of total charge zero. This zero-charge configuration uplifts to a 5D metric without naked singularities, thus avoiding the curvature singularity of the 5D uplift of an isolated charged BPS black hole. Finally, we resolve a puzzle with localization of massless high spin fields on a (putative) Randall-Sundrum 2 construction based on Vasiliev?s high spin theories. We show that while high spin fields do localize, the gauge symmetry that ensures decoupling of their unphysical polarizations is anomalous. This implies that the high spin fields must acquire a mass.     

Diffusion-weighted MRI: influence of intravoxel fat signal and breast density on breast tumor conspicuity and apparent diffusion coefficient measurements

Promising recent investigations have shown that breast malignancies exhibit restricted diffusion on diffusion-weighted imaging (DWI) and may be distinguished from normal tissue and benign lesions in the breast based on differences in apparent diffusion coefficient (ADC) values. In this study, we assessed the influence of intravoxel fat signal on breast diffusion measures by comparing ADC values obtained using a diffusion-weighted single shot fast spin-echo sequence with and without fat suppression. The influence of breast density on ADC measures was also evaluated. ADC values were calculated for both tumor and normal fibroglandular tissue in a group of 21 women with diagnosed breast cancer. There were systematic underestimations of ADC for both tumor and normal breast tissue due to intravoxel contribution from fat signal on non–fat-suppressed DWI. This ADC underestimation was more pronounced for normal tissue values (mean difference=40%) than for tumors (mean difference=27%, P<.001) and was worse in women with low breast tissue density vs. those with extremely dense breasts (P<.05 for both tumor and normal tissue). Tumor conspicuity measured by contrast-to-noise ratio was significantly higher on ADC maps created with fat suppression and was not significantly associated with breast density. In summary, robust fat suppression is important for accurate breast ADC measures and optimal lesion conspicuity on DWI.