Investigation of macro-/mesoporous Re<Subscript>2</Subscript>O<Subscript>7</Subscript>/Al<Subscript>2</Subscript>O<Subscript>3</Subscript> catalysts prepared by a particle-template method for butylene metathesis

Macro-/mesoporous Al₂O₃ supports were prepared by using monodisperse polystyrene (PS) microspheres as a template. The pore volume and BET surface area of the Al₂O₃ supports increased considerably with increasing amounts of the PS microspheres; further investigation showed that PS template only increased the volume of macro-pores but did not change the volume of meso-pores or micro-pores. Macro-/mesoporous Re₂O₇/Al₂O₃ metathesis catalysts were prepared through loading Re₂O₇ onto the as-prepared macro-/mesoporous Al₂O₃ supports, and their catalytic performance was tested in a fixed-bed tubular reactor using the metathesis of normal butylenes as a probe reaction. The results showed that the prepared macro-/mesoporous Re₂O₇/Al₂O₃ catalyst had high activity with consistent selectivity; propylene and pentene accounted for more than 90 wt% of the metathesis products, while the amount of ethylene plus hexane was less than 10 wt%, the majority of which was hexane. These Re₂O₇/Al₂O₃ catalysts had not only higher activity, but also longer working life span and higher tolerance to carbon residues than conventional Re₂O₇/Al₂O₃ catalysts.     

Silver porous nanotube built three-dimensional films with structural tunability based on the nanofiber template-plasma etching strategy

A facile and high-throughput strategy is presented to fabricate three-dimensional (3D) hierarchically porous Ag films, with clean surfaces, via plasma etching Ag-coated electrospun nanofiber template. The films are built of Ag porous nanotubes and are homogeneous in macro-size but rough and porous in nanoscale. Each nanotube-block is micro/nanostructured with evenly distributed nanopores on the tube walls. The film architecture (or the shape, arrangement, and distribution density of porous nanotubes; the number and size of nanopores) can be easily controlled by the nanofiber-template configuration, Ag coating, and plasma etching conditions. Such hierarchically porous films could be very useful, such as in catalysis, sensors, and nanodevices. They have exhibited significantly structurally enhanced surface-enhanced Raman scattering performance with good stability and reproduction, and shown the possibility of molecule-level detection. Also, the strategy is universal for fabricating other hierarchically structured 3D metal porous films, such as porous Ag hollow sphere arrays.     

木犀草素与胞嘧啶相互作用的理论研究

采用密度泛函理论中的B3LYP方法,在6-31＋G＊基组水平上对木犀草素、胞嘧啶、木犀草素-胞嘧啶复合物进行结构优化和振动频率分析,得到了12种稳定复合物.并应用分子中的原子理论（AIM）分析、自然键轨道（NBO）理论分析得到复合物氢键性质和特征.通过基组重叠误差（BSSE）校正后的相互作用能、成键临界点电荷密度、二阶...     

Structural characterization of micelles formed of cholesteryl-functionalized cyclodextrins

Amphiphilic cholesteryl 2,6-di-O-methyl-β-cyclodextrins (chol-DIMEB) can self-aggregate into spherical micelles of noteworthy potential for drug delivery. All-atom molecular dynamics simulations of chol-DIMEB micelles consisting of 3-24 monomers have been performed in aqueous solution. chol-DIMEB exhibits a pronounced tendency to self-assemble into core-shell structures. van der Waals interactions within the cholesteryl nucleus constitute the main driving force responsible for the formation of the micelle. The calculated radii of the hydrophobic core and of the hydrophilic shell for the micellar structure formed by 24 monomers agree well with the experiment. The cyclodextrin moieties are found to be exposed toward the aqueous medium and possess the appropriate flexibility to capture drugs in an effective fashion. Analysis of the solvent accessible surface area and hydration number indicates that the micelles are highly hydrosoluble species and can, therefore, enhance significantly the aqueous solubility of lipophilic drugs. In addition, the spatial structure of the micelles is suggestive of multiple potential drug binding sites. The present contribution unveils how micelles endowed with specific characteristics can form, while opening exciting perspectives for the design of novel micellar nanoparticles envisioned to be drug carriers of high potential.     

Anisotropic wetting on checkerboard-patterned surfaces

A series of surfaces with microscale checkerboard patterns consisting of continuous central lines and discontinuous lateral lines were fabricated. The surface wetting properties of these checkerboard patterns were found to be anisotropic. The central continuous lines were found to have a strong influence on the dynamic wetting properties and moving trajectories of the water droplets. The droplets move more easily in the direction parallel to the central continuous lines and less easily in the direction perpendicular to the central continuous lines. Meanwhile, the droplets' moving path tends to incline toward the central continuous lines from a tilting direction. When the microsurface was modified with a layer of nanowire, the surface wettability was found to be isotropic and superhydrophobic.     

Synergistic antibacterial brilliant blue/reduced graphene oxide/quaternary phosphonium salt composite with excellent water solubility and specific targeting capability

A water-soluble brilliant blue/reduced graphene oxide/tetradecyltriphenylphosphonium bromide composite (BB-rGO-TTP) was prepared by using noncovalent brilliant blue-functionalized reduced graphene oxide (BB-rGO) as the tetradecyltriphenylphosphonium bromide (TTP) carrier. Antibacterial performance of this novel composite was investigated for both Gram-positive and Gram-negative bacteria. The results showed that the novel BB-rGO-TTP, combing the advantages of graphene and TTP, displayed excellent synergistic antibacterial activity, specific targeting capability, water solubility, and mild cytotoxicity, suggesting the great potential application as sprayable graphene-based antibacterial solutions.     

Molecular tilting and its impact on frictional properties of n-alkane self-assembled monolayers

Hydrophobic, methyl-terminated self-assembled monolayer (SAM) surfaces can be used to reduce friction. Among methyl-terminated SAMs, the frictional properties of alkanethiol SAMs and silane SAMs have been well-studied. In this research, we investigated friction of methyl-terminated n-hexatriacontane (C36) SAM and compared its friction properties with the alkanethiol and silane SAMs. Alkane SAM does not have an anchoring group. The alkane molecules stand on the surface by physical adsorption, which leads to a higher surface mobility of alkane molecules. We found that C36 SAM has a higher coefficient of friction than that of octadecyltrichlorosilane (OTS) silane. When an atomic force microscope (AFM) tip was swiped across the alkane SAM with a loading force, we found that the alkane SAM can withstand the tip loading pressure up to 0.48 GPa. Between 0.48 and 0.49Ga, the AFM tip partially penetrated the SAM. When the tip moved away, the deformed SAM healed and maintained the structural integrity. When the loading pressure was higher than 0.49 GPa, the alkane SAM was shaved into small pieces by the tip. In addition, we found that the molecular tilting of C36 molecules interacted with the tribological properties of the alkane SAM surface. On one hand, a higher loading force can push the rod-like alkane molecules to a higher tilting angle; on the other hand, a higher molecular tilting leads to a lower friction surface.     

Biomimetic anchors for antifouling and antibacterial polymer brushes on stainless steel

Barnacle cement (BC) was beneficially applied on stainless steel (SS) to serve as the initiator anchor for surface-initiated polymerization. The amine and hydroxyl moieties of barnacle cement reacted with 2-bromoisobutyryl bromide to provide the alkyl halide initiator for the surface-initiated atom transfer radical polymerization (ATRP) of 2-hydroxyethyl methacrylate (HEMA). The hydroxyl groups of HEMA polymer (PHEMA) were then converted to carboxyl groups for coupling of chitosan (CS) to impart the SS surface with both antifouling and antibacterial properties. The surface-functionalized SS reduced bovine serum albumin adsorption, bacterial adhesion, and exhibited antibacterial efficacy against Escherichia coli (E. coli). The effectiveness of barnacle cement as an initiator anchor was compared to that of dopamine, a marine mussel inspired biomimetic anchor previously used in surface-initiated polymerization. The results indicate that the barnacle cement is a stable and effective anchor for functional surface coatings and polymer brushes.     

Biofunctionalization of a "clickable" organic layer photochemically grafted on titanium substrates

We have developed a general method combining photochemical grafting and copper-catalyzed click chemistry for biofunctionalization of titanium substrates. The UV-activated grafting of an α,ω-alkenyne onto TiO(2)/Ti substrates provided a "clickable" thin film platform. The selective attachment of the vinyl end of the molecule to the surface was achieved by masking the alkynyl end with a trimethylgermanyl (TMG) protecting group. Subsequently, various oligo(ethylene glycol) (OEG) derivatives terminated with an azido group were attached to the TMG-alkynyl modified titanium surface via a one-pot deprotection/click reaction. The films were characterized by X-ray photoelectron spectroscopy (XPS), contact angle goniometry, ellipsometry, and atomic force microscopy (AFM). We showed that the titanium surface presenting click-immobilized OEG substantially suppressed the nonspecific attachment of protein and cells as compared to the unmodified titanium substrate. Furthermore, glycine-arginine-glycine-aspartate (GRGD), a cell adhesion peptide, was coimmobilized with OEG on the platform. We demonstrated that the resultant GRGD-presenting thin film on Ti substrates can promote the specific adhesion and spreading of AsPC-1 cells.     

In-site mineralization of amorphous calcium carbonate particles: A facile and efficient approach to fabricate poly(l-lactic acid) based hybrids

The aim of this investigation is to obtain a polymer-based hybrid material with biodegradability, biocompatibility, and good mechanical properties and this object was realized via. in-situ introduction of the unmodified calcium carbonate (CaCO₃) into a poly(l-lactic acid) (PLLA) matrix. As verified by the measurements from scanning electron microscopy (SEM), optical microscopy, dynamic mechanical analysis (DMA) and thermogravimetric analysis (TGA), the hybrid films which possesses a uniform dispersion of calcium carbonate CaCO₃ in nano-meter scale, mechanically robustness and thermal stability could be fabricated by a mineralization-alike process. For example, the storage modulus increases from 441 MPa of neat PLLA to 1034 MPa of hybrid film containing 2% (w/w) CaCO₃. In addition, the hybrid films display a significant improvement in its UV-exposure resistance.