聚合物熔体界面扩散理论与研究方法

本文结合与聚合物加工过程密切相关的界面扩散问题,从动力学和热力学两方面综述了与聚合物界面互扩散相关的基础理论.结合在聚合物界面扩散方面的研究进展,系统介绍了聚合物熔体界面扩散的常用研究方法.对其中的流变学方法的原理及进展作了重点论述,该方法不仅可以有效表征聚合物熔体界面扩散的动力学过程,进一步从分子动力学角度发展并完善聚合物扩散理论,而且对于聚合物加工成型过程的界面结构设计和性能优化起到关键的指导作用.本文最后提出了聚合物熔体界面扩散研究中存在的问题并对其前景进行了展望.     

镁电解槽中制备镁稀土合金的电解工艺及机制研究

在模拟镁电解槽中,采用电解法制备出稀土含量<10%的镁稀土合金;研究了熔盐中RECl3和CaCl2的含量、电解温度和阴极电流密度对合金中RE含量和电流效率的影响。并采用循环伏安实验和还原实验研究电解制备镁稀土合金的机制。研究结果表明,电解制备镁稀土合金最佳的工艺条件为:熔盐中RECl3和CaCl2的含量分别为3%和10%(质量分数),电解温度为948 K,阴极电流密度约为8 A.cm-2。其电解过程机制为:阴极上只电解出金属镁,而后金属镁把稀土元素还原出来,形成镁稀土合金。     

Functionalized graphene quantum dots loaded with free radicals combined with liquid chromatography and tandem mass spectrometry to screen radical scavenging natural antioxidants from Licorice and Scutellariae

A novel screening method was developed for the detection and identification of radical scavenging natural antioxidants based on a free radical reaction combined with liquid chromatography with tandem mass spectrometry. Functionalized graphene quantum dots were prepared for loading free radicals in the complex screening system. The detection was performed with and without a preliminary exposure of the samples to specific free radicals on the functionalized graphene quantum dots, which can facilitate charge transfer between free radicals and antioxidants. The difference in chromatographic peak areas was used to identify potential antioxidants. This is a novel approach to simultaneously evaluate the antioxidant power of a component versus a free radical, and to identify it in a vegetal matrix. The structures of the antioxidants in the samples were identified using tandem mass spectrometry and comparison with standards. Fourteen compounds were found to possess potential antioxidant activity, and their free radical scavenging capacities were investigated. The order of scavenging capacity of 14 compounds was compared according to their free radical scavenging rate. 4′,5,6,7‐Tetrahydroxyflavone (radical scavenging rate: 0.05253 mL mg^?1 s^?1) showed the strongest capability for scavenging free radicals.     

A Furan-based Phosphaphenanthrene-containing Derivative as a Highly Efficient Flame-retardant Agent for Epoxy Thermosets without Deteriorating Thermomechanical Performances

In order to reduce greenhouse gas emissions, developing flame retardants from bio-based resources has aroused extensive interest in recent years. In this work, we utilized furfural(biomass) and 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide(DOPO) to synthesize a biobased co-curing agent(FGD) to combine with 4,4'-diaminodiphenyl methane(DDM) for obtaining a low-phosphorus loading flame-retardant epoxy thermosets. The introduction of FGD decreased the activation energy of the curing progress, enhanced the mechanical properties of the epoxy thermosets, and did not affect the glass transition temperature of the epoxy thermosets. EP-5.0 had a lower thermal degradation rate and a doubled char yield compared with EP-0. The phosphorus content of EP-5.0 was only 0.45 wt%, while EP-5.0 reached the UL-94 V-0 rating with a high LOI value of 32%. Compared with EP-0, the PHRR of EP-2.5 and EP-5.0 decreased by 22.3% and 31.3%, respectively. The SEM results showed that the addition of FGD made the char residues more uniform and denser, which could effectively prevent combustible volatiles from escaping from the degradation area to the flame area and isolate the heat transfer so that the epoxy thermosets had an excellent flame-retardant performance.     

基于ZIF-8/PAN复合薄膜的柔性丙酮气体传感器

ZIF-8是一种Zn基金属有机骨架材料, 可以吸附丙酮气体从而作为电容式丙酮传感器的气敏材料, 然而ZIF-8的传统使用形式为粉末态, 这导致其不能成为具备柔性的整体, 从而限制了传感器的柔性. 结合包埋种子和二次生长法将ZIF-8与纳米纤维结合成纤维型柔性材料, 并将其作为气敏层制备了柔性电容式丙酮气体传感器. 该传感器在9种常见挥发性有机化合物中表现出良好的选择性, 对250~2000 cm³/m³的丙酮气体具有灵敏的响应、良好的循环响应及长期稳定性. 值得注意的是该柔性传感器不仅在室温下进行传感, 而且在弯折180°的状态下对丙酮气体的响应值与不弯折(0°)状态下几乎一致, 在200次以内的180°弯折-恢复后同样表现出了传感性能的稳定, 表明了其在柔性传感器方面的潜力.     

石墨烯包覆天然球形石墨作为锂离子电池的负极材料，是否需要乙炔黑导电剂？

我们通过包覆炭化的方法制备得到了石墨烯包覆的天然球形石墨(G/SG)材料,并使用扫描电子显微镜、X射线衍射仪以及多种电化学测试手段考察了不同石墨烯含量的复合材料的形貌结构及电化学性能。我们发现,在不添加乙炔黑(AB)的情况下,G/SG复合材料表现出较高的首次库伦效率,很好的循环稳定性和高倍率性能。当石墨烯包覆量为1%时,材料50次循环后的可逆容量可与添加10%AB的天然石墨电极(SG)等同;当石墨烯包覆量为2.5%时,材料的比容量完全高于添加10%AB的石墨电极。材料电化学性能的改善归因于石墨烯的包覆。一方面,石墨烯的柔软可变性可以保证天然石墨颗粒在充放电过程中的结构完整性,从而有效改善材料的循环稳定性;另一方面,石墨烯的存在提高了电极的导电性,促进更好导电网络的形成。因此,石墨烯包覆天然球形石墨材料中,石墨烯不仅是活性物质,也发挥导电剂的作用。当添加5%的乙炔黑时,在50 mA·g^-1电流循环50次后,5%G/SG电极的可逆容量从381.1 mAh·g^-1提高到404.5 mAh·g^-1,在1 A·g^-1电流时可逆容量从82.5 mAh·g^-1提高到101.9 mAh·g^-1,这表明G/SG电极仍然需要乙炔黑导电剂。乙炔黑颗粒填充在复合材料的空隙中,通过点接触的形式连接到G/SG颗粒,与石墨烯协同作用形成了更加有效的导电网络。尽管石墨烯包覆和乙炔黑添加对天然石墨电极具有积极的影响,例如增加了天然石墨电极的导电性和储锂性能(包括可逆容量,倍率性能和循环性能),但随着石墨烯或乙炔黑的增加,电极密度通常会降低。因此,在实际应用中应考虑石墨负极材料的质量和体积容量的平衡。这些结果对天然石墨的进一步商业应用具有重要意义。我们的工作为天然石墨电极在锂电池中的电化学行为提供了一种新的认识,并且有助于制备更高性能的负极材料。     

Development of a method to screen and isolate xanthine oxidase inhibitors from black bean in a single step: Hyphenation of semipreparative liquid chromatography and stepwise flow rate countercurrent chromatography

Black bean, in which isoflavones are the main active constituent, also contains saponins and monoterpenes. Soybean isoflavone is a secondary metabolite that is formed during the growth of soybean; it exhibits antioxidant and cardiovascular activities and traces estrogen-like effects. In this study, black bean isoflavones were extracted with n-butanol, and ultrafiltration–liquid chromatography–mass spectrometry was used to screen their activity. Subsequently, the inhibitors were isolated and purified using semipreparative liquid chromatography and stepwise flow rate countercurrent chromatography. Thereafter, five active compounds were identified using mass spectrometry and nuclear magnetic resonance experiments. Finally, the inhibition types of the xanthine oxidase inhibitors were determined using enzymatic kinetic studies. The IC₅₀ values of daidzin, glycitein-7-O-glucoside, genistin, daidzein, and genistein were determined to be 35.08, 56.22, 30.76, 68.79, and 95.37 μg/mL, respectively. Daidzin, genistin, and daidzein exhibited reversible inhibition, whereas glycitein-7-O-glucoside and genistein presented irreversible inhibition. This novel approach, which was based on ultrafiltration–liquid chromatography–mass spectrometry and stepwise flow rate countercurrent chromatography, is a powerful method for screening and isolating xanthine oxidase inhibitors from complex matrices. The study of enzyme inhibition types is helpful for understanding the underlying inhibition mechanism. Therefore, a beneficial platform was developed for the large-scale production of bioactive and nutraceutical ingredients.     

An efficient strategy based on two-stage chromatography and in vitro evaluation for rapid screening and isolation of acetylcholinesterase inhibitors from Scutellaria baicalensis Georgi

The extraction of Scutellaria baicalensis Georgi was investigated using the response surface methodology-genetic algorithm mathematical regression model, and the extraction variables were optimized to maximize the flavonoid yield. Furthermore, a simple and efficient ultrafiltration–liquid chromatography–mass spectrometry and molecular docking methods were developed for the rapid screening and identification of acetylcholinesterase inhibitors present in Scutellaria baicalensis Georgi. Subsequently, four major chemical constituents, namely baicalein, norwogonin, wogonin, and oroxylin A, were identified as potent acetylcholinesterase inhibitors. This novel approach, involving the use of ultrafiltration–liquid chromatography–mass spectrometry and molecular docking methods combined with stepwise flow rate counter-current chromatography and semi-preparative high-performance liquid chromatography, could potentially provide a powerful tool for the screening and extraction of acetylcholinesterase inhibitors from complex matrices and be a useful platform for the production of bioactive and nutraceutical ingredients.     

Generation of Glycosyl Radicals from Glycosyl Sulfoxides and Its Use in the Synthesis of C‐linked Glycoconjugates

We here report glycosyl sulfoxides appended with an aryl iodide moiety as readily available, air and moisture stable precursors to glycosyl radicals. These glycosyl sulfoxides could be converted to glycosyl radicals by way of a rapid and efficient intramolecular radical substitution event. The use of this type of precursors enabled the synthesis of various complex C‐linked glycoconjugates under mild conditions. This reaction could be performed in aqueous media and is amenable to the synthesis of glycopeptidomimetics and carbohydrate‐DNA conjugates.     

Monolayer 1T and 1T′ MoSO as Promising Electrocatalyst for Hydrogen Evolution based on First Principle Calculations

Molybdenum disulfide (MoS₂) has been regarded as one of the most promising candidates for replacing Pt group noble metals as an efficient electrocatalyst to enhance the hydrogen evolution reaction (HER) in consideration of its relatively high earth abundance. Recent studies show that the catalytic efficiency of MoS₂ for HER can be promoted by the presence of 1T-phase MoS₂. It is hard to precisely control the formation of 1T-MoS₂, however, due to its metastability relative to 2H-MoS₂. Elevating the stability of 1T phase allotrope is therefore of great importance and could be realized by replacing divalent S with monovalent elements or groups according to crystal field theory, which has been demonstrated through our first-principles density functional theory (DFT) calculation results. Differential Gibbs free energy analysis for hydrogen adsorption (ΔG_H*) suggest that 1T and 1T′ MoSO (O doped MoS₂) might be taken as potential candidate catalysts for HER process with better performance than 1T and 1T′ MoS₂. We also propose a probable approach to synthesize 1T and 1T′ MoSO under oxidation circumstance environment of graphene oxide.