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991.
Xia N Shumaker-Parry JS Zareie MH Campbell CT Castner DG 《Langmuir : the ACS journal of surfaces and colloids》2004,20(9):3710-3716
The ability of streptavidin (SA) to simultaneously bind four biotins is often used in linker layers, where a biotinylated molecule is linked to a biotin-functionalized surface via SA. For biosensor and array applications, it is desirable that the SA linker layer be stable to drying and rehydration. In this study it was observed that a significant decrease in binding capacity of a SA layer occurred when that layer was dried. For this study a SA linker layer was constructed by binding SA to a biotin-containing alkylthiolate monolayer (BAT/OEG) self-assembled onto gold. Its stability after drying was investigated using surface plasmon resonance (SPR). Approximately a quarter of the SA layer was removed from the BAT/OEG surface upon drying and rehydration, suggesting disruption of SA-biotin binding when dry. This resulted in the dried SA layer losing approximately 40% of its biotinylated ferritin (BF) binding capacity. Coating the layer with trehalose before drying was found to inhibit the loss of SA from the BAT/OEG surface. SPR showed that the trehalose-protected SA linker layer retained approximately 91% of its original BF binding capacity after drying and rehydration. Atomic force microscopy, which was used to image individual surface-bound SA and BF molecules, qualitatively confirmed these observations. 相似文献
992.
993.
废轮胎热解炭的分析及其活化特性的研究 总被引:1,自引:5,他引:1
用常规分析方法分析了废轮胎热解炭的成分和性质,用X射线能谱分析法、压汞法、N2吸附法等测定了热解炭的孔隙结构特性,并用CO2、含2%氧气的氮气流和水蒸气等活化气体对热解炭进行活化方面的研究。结果表明,热解炭灰分和硫含量比较高;两种不同粒径热解炭的比孔容积均在r≈25 nm处有最大值;在相同活化时间和活化剂流速下,温度越高,活化炭烧失率越大,比表面积也越大;在一定温度和活化剂流速下,烧失率和比表面积随着活化时间的增加而增大;对所有试验工况,烧失率越大,活化炭比表面积也越大。总体上水蒸气活化炭与CO2的活化效果较好,而含2%O2的氮气流活化的效果则次之。活化炭与商业活性炭的比较显示,前者具有较发达的孔隙结构,在进行大分子物质吸附时,具有替代商业活性炭的潜力。 相似文献
994.
Pu Chen Jiang Nan Yan Hu Yifan Kang Bo Wang Yangmin Ma Michal Szostak 《Chemical science》2021,12(2):803
A metal-free C–H [5 + 1] annulation reaction of 2-arylanilines with diazo compounds has been achieved, giving rise to two types of prevalent phenanthridines via highly selective C–C cleavage. Compared to the simple N–H insertion manipulation of diazo, this method elegantly accomplishes a tandem N–H insertion/SEAr/C–C cleavage/aromatization reaction, and the synthetic utility of this new transformation is exemplified by the succinct syntheses of trisphaeridine and bicolorine alkaloids.A metal-free C–H [5 + 1] annulation reaction of 2-arylanilines with diazo compounds has been achieved, giving rise to two types of prevalent phenanthridines via highly selective C–C cleavage. 相似文献
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998.
Yan‐Ting He Wan‐Long Pan Ying‐Nan Chi Kun‐Lin Huang Chang‐Wen Hu 《Acta Crystallographica. Section C, Structural Chemistry》2007,63(4):m161-m162
In the binuclear title molecule, [Zn2(C9H7NO4)Cl2(C12H8N2)2], the two metal centres are bridged by a 2,6‐dimethylpyridine‐3,5‐dicarboxylate ligand. The binuclear unit is extended to form a two‐dimensional supramolecular motif viaπ–π stacking interactions between neighbouring phenanthroline rings. 相似文献
999.
WeiRongYAN YaoTingYU NanDONG 《中国化学快报》2003,14(7):693-696
Myasthenia Gravis (MG) is an organ specific autoimmune disease mediated by autoantibodies (AChR Ab) against the acetylcholine receptor (AChR). Literature reported that the AChR Ab can be removed by absorbent linked with tryotophan.It was studied in detail in our lab. With the aid of computer, we docked some ligandsinto AChR Ab, and the results fromscores of docking under different generations showed that therewas no specific binding between tryptophan and scFv fragment just as the binding between antigen-antibody. The interaction between Trp and immunoglobulin was a broad-spectntm binding. 相似文献
1000.
Xin‐Ming Zhou Zheng‐Yu Zhou Qun‐Yan Wu Abraham F. Jalbout Nan Zhang 《International journal of quantum chemistry》2006,106(2):514-525
All species involved in the multi‐channel reaction of CH3O2 with HO2 have been investigated using density functional theory (DFT). The molecular geometries for various species are optimized employing the B3LYP method implementing the 6‐311++G** basis set. The relative energies of all species are calculated at the same level theory. The results show that there are two kinds of channels: singlet and triplet. The singlet channel involves four intermediates and six transition states. The triplet channel includes two intermediates and two transition states. There are four kinds of reaction products: CH3OOH + 1O2, CH3OH + O3, CH4 + 2O2, and CH3OOH + 3O2. The vibrational mode analysis is used to elucidate the relationships of the intermediates, the transition states, and the products. The extensive investigation shows that the reaction mechanism is reliable. © 2005 Wiley Periodicals, Inc. Int J Quantum Chem, 2006 相似文献