全文获取类型
收费全文 | 72篇 |
免费 | 2篇 |
专业分类
化学 | 24篇 |
数学 | 13篇 |
物理学 | 37篇 |
出版年
2021年 | 4篇 |
2020年 | 3篇 |
2019年 | 1篇 |
2018年 | 2篇 |
2015年 | 4篇 |
2013年 | 2篇 |
2012年 | 4篇 |
2010年 | 11篇 |
2009年 | 3篇 |
2008年 | 3篇 |
2007年 | 3篇 |
2006年 | 2篇 |
2005年 | 1篇 |
2004年 | 2篇 |
2003年 | 1篇 |
2002年 | 3篇 |
2001年 | 2篇 |
2000年 | 2篇 |
1997年 | 1篇 |
1996年 | 2篇 |
1995年 | 5篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1991年 | 3篇 |
1988年 | 1篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1981年 | 1篇 |
1979年 | 2篇 |
1967年 | 1篇 |
排序方式: 共有74条查询结果,搜索用时 281 毫秒
61.
We consider label setting algorithms for the multi-objective shortest path problem with any number of sum and bottleneck objectives. We propose a weighted sum aggregate ordering of the labels, specifically tailored to combine sum and bottleneck objectives. We show that the aggregate order leads to a consistent reduction of solution times (up to two-thirds) with respect to the classical lexicographic order. 相似文献
62.
A structure optimization method with ionization energy constraint is developed to explore structures with specific ionization energy. The Levine-Coe-Martínez penalty function (J Phys Chem B 2008, 112, 405) was adopted, and the penalty function includes a predefined core-ionization energy and inner-shell ionization energy. For an SN2 reaction, isomerization of a platinum complex, a proton transfer reaction, and carbon monoxide adsorption on a palladium cluster, the present method was tested, and the targeted energy minima were obtained as designated by the input ionization energy. The shape of the objective function, the parameters in the penalty function, and structural changes during the optimization process were discussed. An automated parameter setting and possible problems are discussed for future direction. © 2018 Wiley Periodicals, Inc. 相似文献
63.
Tsang MB Hsi WC Lynch WG Bowman DR Gelbke CK Lisa MA Peaslee GF Kunde GJ Begemann-Blaich ML Hofmann T Hubele J Kempter J Kreutz P Kunze WD Lindenstruth V Lynen U Mang M Müller WF Neumann M Ocker B Ogilvie CA Pochodzalla J Rosenberger F Sann H Schüttauf A Serfling V Stroth J Trautmann W Tucholski A Wörner A Zude E Zwieglinski B Aiello S Immé G Pappalardo V Raciti G Charity RJ Sobotka LG Iori I Moroni A Scardoni R Ferrero A Seidel W Blaich T Stuttge L Cosmo A Friedman WA Peilert G 《Physical review letters》1993,71(10):1502-1505
64.
Ogilvie CA Adloff JC Begemann-Blaich M Bouissou P Hubele J Imme G Iori I Kreutz P Kunde GJ Leray S Lindenstruth V Liu Z Lynen U Meijer RJ Milkau U Müller WF Ng C Pochodzalla J Raciti G Rudolf G Sann H Schüttauf A Seidel W Stuttge L Trautmann W Tucholski A 《Physical review letters》1991,67(10):1214-1217
65.
Mastinu PF Belkacem M D'Agostino M Bruno M Milazzo PM Vannini G Bowman DR Colonna N Dinius JD Ferrero A Fiandri ML Gelbke CK Glasmacher T Gramegna F Handzy DO Horn D Hsi WC Huang M Iori I Kunde GJ Lisa MA Lynch WG Margagliotti GV Montoya CP Moroni A Peaslee GF Petruzzelli F Rui R Schwarz C Tsang MB Williams C Latora V Bonasera A 《Physical review letters》1996,76(15):2646-2649
66.
CH Activation Generates Period‐Shortening Molecules That Target Cryptochrome in the Mammalian Circadian Clock 下载免费PDF全文
Tsuyoshi Oshima Dr. Iori Yamanaka Dr. Anupriya Kumar Dr. Junichiro Yamaguchi Dr. Taeko Nishiwaki‐Ohkawa Kei Muto Rika Kawamura Dr. Tsuyoshi Hirota Prof. Dr. Kazuhiro Yagita Prof. Dr. Stephan Irle Prof. Dr. Steve A. Kay Prof. Dr. Takashi Yoshimura Prof. Dr. Kenichiro Itami 《Angewandte Chemie (International ed. in English)》2015,54(24):7193-7197
The synthesis and functional analysis of KL001 derivatives, which are modulators of the mammalian circadian clock, are described. By using cutting‐edge C? H activation chemistry, a focused library of KL001 derivatives was rapidly constructed, which enabled the identification of the critical sites on KL001 derivatives that induce a rhythm‐changing activity along with the components that trigger opposite modes of action. The first period‐shortening molecules that target the cryptochrome (CRY) were thus discovered. Detailed studies on the effects of these compounds on CRY stability implicate the existence of an as yet undiscovered regulatory mechanism. 相似文献
67.
Iori Morita Takahiro Mori Takaaki Mitsuhashi Shotaro Hoshino Yoshimasa Taniguchi Takashi Kikuchi Kei Nagae Norihiro Nasu Makoto Fujita Tomohiko Ohwada Ikuro Abe 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(10):4017-4022
C–S bond formation reactions are widely distributed in the biosynthesis of biologically active molecules, and thus have received much attention over the past decades. Herein, we report intramolecular C–S bond formation by a P450 monooxygenase, TleB, which normally catalyzes a C−N bond formation in teleocidin biosynthesis. Based on the proposed reaction mechanism of TleB, a thiol-substituted substrate analogue was synthesized and tested in the enzyme reaction, which afforded the unprecedented sulfur-containing thio-indolactam V, in addition to an unusual indole-fused 6/5/8-tricyclic product whose structure was determined by the crystalline sponge method. Interestingly, conformational analysis revealed that the SOFA conformation is stable in thio-indolactam V, in sharp contrast to the major TWIST form in indolactam V, resulting in differences in their biological activities. 相似文献
68.
P. Sapienza R. Coniglione M. Colonna E. Migneco C. Agodi R. Alba G. Bellia A. Del Zoppo R. Finocchiaro V. Greco K. Loukachine C. Maiolino P. Piattelli D. Santonocito P. G. Ventura Y. Blumenfeld M. Bruno N. Colonna M. D’Agostino L. Fabbietti M. L. Fiandri F. Gramegna I. Iori G. V. Margagliotti P. F. Mastinu P. M. Milazzo A. Moroni R. Rui J. A. Scarpaci G. Vannini 《Acta Physica Hungarica A》2002,16(1-4):337-346
Energetic proton emission has been investigated as a function of the centrality in the reaction 58Ni + 58Ni at 30 AMeV. Protons with energy extending up to a relevant fraction of the total available energy in the reaction were measured and studied. The dependence on the reaction centrality has been extensively investigated and data have been compared with the results of microscopic transport calculations. The more striking observation concerns the extremely energetic proton (ENN P ≥ 130 MeV) multiplicity which is found to increase almost quadratically with the number of participant nucleons thus indicating the onset of a mechanism beyond one and two-body dynamics. 相似文献
69.
Renato Millioni Manuela Miuzzo Stefano Sbrignadello Ellen Murphy Lucia Puricelli Andrea Tura Elisa Bertacco Marcello Rattazzi Elisabetta Iori Paolo Tessari 《Electrophoresis》2010,31(8):1311-1317
2‐DE is a fundamental technology used in proteomics research. However, despite its high capacity to simultaneously separate several proteins for subsequent identification and quantitative comparison studies, a drawback for this technique is its limited reproducibility, especially when comparing data from different laboratories. 2‐DE‐related variability can be broadly divided into two categories: experimental and post‐experimental. Experimental variability depends on physical and chemical parameters, whereas post‐experimental variability arises when gels are analyzed by different software packages, particularly when different workflows are followed. In this paper, we compared the analysis performance of two software packages, Delta2D and Proteomweaver, using both standard and experimental gel images. Using standard gel images, the false negative spot count was 50% lower, the false positive count was 77% lower, the true positive count was 19% higher and spot matching was 4% higher in Delta2D when compared to Proteomeweaver. Using experimental gel images, we found that the total amount of time taken to complete the analysis with Delta2D was 30% that of the time needed with Proteomweaver and required fewer user interventions. The differences between ease of use and workflow strategy of these programs is discussed. 相似文献
70.
Hongfei Xi T. Odeh R. Bassini M. Begemann-Blaich A. S. Botvina S. Fritz S. J. Gaff C. Groß G. Immé I. Iori U. Kleinevoß G. J. Kunde W. D. Kunze U. Lynen V. Maddalena M. Mahi T. Möhlenkamp A. Moroni W. F. J. Müller C. Nociforo B. Ocker F. Petruzzelli J. Pochodzalla G. Raciti G. Riccobene F. P. Romano Th. Rubehn A. Saija M. Schnittker A. Schüttauf C. Schwarz W. Seidel V. Serfling C. Sfienti W. Trautmann A. Trzcinski G. Verde A. Wörner B. Zwieglinski 《Zeitschrift für Physik A Hadrons and Nuclei》1997,359(4):397-406
Breakup temperatures were deduced from double ratios of isotope yields for target spectators produced in the reaction 197Au + 197Au at 1000 MeV per nucleon. Pairs of 3,4He and 6,7Li isotopes and pairs of 3,4He and H isotopes (p, d and d, t) yield consistent temperatures after feeding corrections, based on the quantum statistical model, are applied. The temperatures rise with decreasing impact parameter from 4 MeV for peripheral to about 10 MeV for the most central collisions. The good agreement with the breakup temperatures measured previously for projectile spectators at an incident energy of 600 MeV per nucleon confirms the universality established for the spectator decayat relativistic bombarding energies. The measured temperatures also agree with the breakup temperatures predicted by the statistical multifragmentation model. For these calculations a relation between the initial excitation energy and mass was derived which gives good simultaneous agreement for the fragment charge correlations. The energy spectra of light charged particles, measured at τlab = 150°, exhibit Maxwellian shapes with inverse slope parameters much higher than the breakup temperatures. The statistical multifragmentation model, because Coulomb repulsion and sequential decay processes are included, yields light-particle spectra with inverse slope parameters higher than the breakup temperatures but considerably below the measured values. The systematic behavior of the differences suggests that they are caused by light-charged-particle emission prior to the final breakup stage. 相似文献