Synthesis,Structure and Luminescence of a Novel 2D Cadmium Coordination Polymer with a Ligand Generated in situ

The hydrothermal reaction of 1,2-dicyanobenzene with NaN3 in the presence of Cd(NO3)2 affords a novel 2D cadmium tetrazolyl-benzoate,{Cd(tzbz)(H2O)}n (H2tzbz is 2-(5-tetrazolyl)-benzoate). The tzbz ligand is generated in situ through the 2+3 Sharpless cycloaddition reaction and hydrolyzation. Its crystal structure was determined by single-crystal X-ray diffraction method. The crystal crystallizes in the orthorhombic system,space group Pbca with a=9.6659(19),b=7.6366(15),c=25.964(5) ,V=1916.5(7) 3,Z=8,Mr=318.57,Dc= 2.208 g/cm3,F(000)=1232 and μ=2.276 mm-1. The Cd(Ⅱ) atom is coordinated by four tzbz ligands and one water molecule to form a severely distorted pentangle bipyramid. While each tzbz ligand connects to four Cd(Ⅱ) atoms in a μ4-η1,η2,η1,η1,η1 coordination mode to construct a 2D architecture of the title complex. Additionally,the title complex exhibits strong fluorescence at room temperature in the solid state.     

标架形式的简化旋量体系及其对杨振宁方程的应用

本文给出时空流形的一种简化的旋量描述形式。特别是证明了在Newman-Penrose方程中有六个多余的方程。作为对杨振宁引力场方程的应用,求得全部O型和一部分N型“纯粹空间”。     

β微管蛋白中紫杉醇(Taxol)结合腔的性质分析

采用多拷贝同时搜寻法(MCSS), 并结合现有微管抑制剂的SAR及3D-QSAR对β微管蛋白中Taxol(紫杉醇)结合腔的性质进行了分析. 结构研究结果表明, Taxol结合腔以疏水性质为主, 并指出官能团分布的具体位置: 在Phe270上方(Leu361-Pro272-Leu273-Leu228之间)的弧形区域、Asp26羧基下方及其与Glu22羧基之间、M-loop的中部, 以及Asp224内侧且靠近Arg276的胍基的位置. 而Asp224的内侧又是新提出的结合位点. 研究结果符合现有微管抑制剂的SAR, 为现有抗肿瘤药物的结构改造以及小分子微管抑制剂设计提供了理论依据.     

^1^5N标记邻位芳香羟肟配位体的核磁共振研究

利用稳定同位素的磁性和质量同位素效应已成为研究有机结构化学的重要手段。我们为研究部位芳香及其芝渡金属如Cu(Ⅱ),Ni(Ⅱ),Co(Ⅱ),Fe(Ⅱ)配合物的光     

二（胍基）锆配合物的合成和表征

Addition of one equivalent of LiN（i-Pr）2 or LiN（CH2）5 to carbodiimides, RN=C=NR [R=cyclohexyl （Cy）, isopropyl （i-Pr）], generated the corresponding lithium of tetrasubstituted guanidinates {Li[RNC（N R^′2）NR]（THF）}2 [R=i-Pr, N R^′2=N（i-Pr）2 （1）, N（CH2）5 （2）; R=Cy, N R^′2=N（i-Pr）2 （3）, N（CH2）5 （4）]. Treatment of ZrCl4 with freshly prepared solutions of their lithium guanidinates provided a series of bis（guanidinate） complexes of Zr with the general formula Zr[RNC（N R^′2）NR]2Cl2 [R=i-Pr, N R^′2=N（i-Pr）2 （5）, N（CH2）5 （6）; R=Cy, N R^′2=N（i-Pr）2 （7）, N（CH2）5 （8）]. Complexes 1, 2, 5-8 were characterized by elemental analysis, IR and ^1H NMR spectra. The molecular structures of complexes 1, 7 and 8 were further determined by X-ray diffraction studies.     

Solid-phase Synthesis of-Haloaldehydes from Polymer-supported 4-(Phenylseleno)morpholine

Polymer-supported reagents for organic synthesis are enjoying a renewed popularity with the emergence of combinatorial chemistry in recent years1. 4-(Arylseleno)morpholines formed in situ are useful -seleno-introducing reagents for saturated aldehydes2. -Sele- noaldehydes, as a frequently used intermediates, can be converted into -haloaldehydes by halogenating reaction3. However, organic selenium reagents always have a foul smell and are quite toxic, which is often problematic in organic sy…     

杂多酸盐(TBA)_n[XW_9Mo_2(CH_3SiOSiCH_3)O_(39)]的合成和表征

具有Keggin衍生结构,以α-[SiW_(11)(RSiOSiR)O_(39)]~(4-)(R=C_2H_5、C_6H_5、NC(CH_2)_3、C_3H_5)为阴离子的杂多酸盐已有报道,但以[XW_9Mo_2(RSiOSiR)O_(39)]~(n-)为阴离子的杂多酸盐尚未见报道。本文首次合成六种以[XW_9Mo_2(CH_3SiOSiCH_3)O_(39)]~(n-)以及[XW_(11)(CH_3SiOSiCH_3)O_(39)]~(n-),(X=Si,P,Ge)为阴离子的杂多酸四丁基铵(TBA)盐,并对它们进行了表征。     

29Si NMR谱对[SiW11(CH3SiOSiCH3)O39]4-结构的验证

Keggin结构杂多酸的有机衍生物[SiW_(11)(RSiOSiR)O_(39)]~(4-)(R=C_2H_5、C_6H_5、NC(CH_2)_3、C_3H_7)已有报道,根据其红外光谱中出现1040cm~(-1)(Si-O-Si的振动峰),Knoth提出了图1的结构。从中可以看出RSiOSiR基占据了Keggin结构杂多酸[SiW_(11)O_(39)]~(8-)的空缺齿顶位置。当然处于齿顶位置的硅原子和中心位置的硅原子的化学环境显然是不同的,所以可用~(29)Si NMR来鉴定这两种硅原子,并推测其结构。     

希土化合物对离体巨噬细胞的影响

本文应用细胞培养法和单细胞阳离子测定系统研究了希土化合物以地巨噬细胞的影响，结果表明，在培养介质中ＳｍＣｌ３和Ｙｃｌ３的浓度大于１ｍｍｏｌ．ｄｍ＾－３时，有明显的细胞毒性，Ｙｃｌ３的细胞毒性大于ＳｍＣｌ３，ＳｍＣｌ３和ＹＣｌ３的细胞毒性明显大于Ｓｍ（Ａｌａ）３Ｃｌ３和Ｙ（Ａｌａ）２Ｃｌ３。希土化合物的作用使细胞（Ｃａ＾２＋ｉ）升高；毒性越大，Ｃａ＾２＋ｉ升高越甚。低浓度Ｓｍ＾３＋和Ｙ６３＋对细胞膜     

PP/PS共混体系相结构形成与演变

以连续共混过程中间歇出料法研究了聚丙烯(PP)/聚苯乙烯(PS)体系共混过程中的扫描电镜图样演化过程,利用小角激光散射(SALS)证明了PP/苯乙烯-乙烯-丙烯嵌段共聚物(SEP)/PS体系的部分相容性,同时说明SALS研究聚合物熔体动态过程的有效性.针对扫描电镜图样,用重心粒径dg这一结构参数研究了PP/PS体系共混过程,利用分布函数求取了分散相PP分形维数,对共混过程中相分散进行了研究.