烷基和烷基苯磺酸钠系列的反相高效液相色谱法

用移动相中含有磷酸二氢钠的反相高效液相色谱法分析了烷基磺酸钠和烷基苯磺酸钠。对前者用电导检测器直接进行检测(无抑制柱),后者用紫外检测器检测。对几种商品十二烷基苯磺酸钠的组分和微乳液中十二烷基磺酸钠的含量进行了测定。得到了满意的结果。     

介质对配合物稳定性的影响——Ⅱ.Cu(SCN)+—NaNO3—二氧六环—水体系

本文用分光光度法确定了25℃时配阳离子Cu(SCN)~+在NaNO_3—二氧六环—H_2O介质中的稳定常数。溶剂组成变化范围为0,5,10,15和20wt％二氧六环,离子强度范围为0.2～3.0moledm~(-3),溶液的pH=1.5～1.6。本文提出了基于Pitzer方程式的最小二乘多项式逼近法,确定出各种不同组成混合溶剂中配合物的热力学稳定常数。讨论了该常数和一级介质效应与溶剂组成和介电常数的关系。     

4′-乙酰基苯并-15-冠-5缩氨基硫脲的微波合成及晶体结构

硫脲衍生物主要通过氢键与阴离子相互作用达到识别的目的，冠醚和硫脲两个主体分子亚单元之间的协同作用往往使冠醚和硫脲表现出对某些客体更加优越的络合识别能力，我们在以前工作的基础上，微波辐射下合成了标题化合物并用红外光谱、核磁共振氢谱、元素分析、X射线单晶衍射对其结构进行了表征，欲进一步研究其对阳离子和阴离子识别的双重功效。     

一种具有二维状组装体结构的氢键结合超分子水凝胶的制备

近年来,基于低分子量有机凝胶因子(low molecular mass organic gelators)[1]形成的超分子水凝胶得到了广泛关注.     

Linking Chiral Clusters with Molybdate Building Blocks: From Homochiral Helical Supramolecular Arrays to Coordination Helices

The synthesis of four new oxo‐centered Fe clusters ( 1 a – c , 2 ) of the form [Fe^III₃(μ₃‐O)(CH₂=CHCOO)₆] with acrylate as the bridging ligand gives rise to potentially intrinsically chiral oxo‐centered {M₃} trimers that show a tendency to spontaneously resolve upon crystallization. For instance, 1 a , [Fe^III₃(μ₃‐O)(CH₂=CHCOO)₆‐(H₂O)₃]⁺, crystallizes in the chiral space group P3₁ as a chloride salt. Crystallization of 1 b , [Fe₃(μ₃‐O)(C₂H₃CO₂)₆(H₂O)₃]NO₃?4.5H₂O, from aqueous solution followed by recrystallization from acetonitrile also gives rise to spontaneous resolution to yield the homochiral salt [Fe₃(μ₃‐O)(C₂H₃CO₂)₆‐(H₂O)₃]NO₃?CH₃CN of 1 c (space group P2₁2₁2₁). Furthermore, the reaction of 1 a with hexamolybdate in acetonitrile gives the helical coordination polymer {[(Fe₃(μ₃‐O)L₆(H₂O))(MoO₄)‐(Fe₃(μ₃‐O)L₆(H₂O)₂)]?2CH₃CN?H₂O}_∞ 2 (L: H₂C?CHCOO), which crystallizes in the space group P2₁. The nature of the ligand geometry allows the formation of atropisomers in both the discrete ( 1 a – c ) and linked {Fe₃} clusters ( 2 ), which is described along with a magnetic analysis of 1 a and 2 .     

Analysis of Chlorogenic Acid in Herbal Medicines by Capillary Electrophoresis

Atpresent,thecommonlyusedmethodforanalyzingherbalmedicinesishighperformanceliquidchromatography(HPLC).However,theuseofHPLCisrestrictedformanyreasons.Themostseriousproblemisthatthechromatographiccolumniseasilycontaminated.ComparedwithHPLC,capillaryelectrophoresis(CE)ischaracterizedwithhighefficiency,rapidity,lowcostandmultiplemodestobechosen.Inaddition,thecapillarycanbeeasilyregenerated.SoCEisidealforanalyzing"dirty"samples,suchasChineseherbalmedicines.Infact,studiesintheareaarebecoming…     

Microstructure and Ion Exchange in Stearic Acid Langmuir-Blodgett Films Studied by Fourier Transform Infrared-Attenuated Total Reflection Spectroscopy

Fourier transform infrared-attenuated total reflection (FTIR-ATR) spectra have been recorded of 11-layer Langmuir-Blodgett (LB) films of stearic acid deposited at various surface pressures (0.1, 15, and 35 mN/m), and the molecular orientation angles were evaluated quantitatively, which supplied insight into the molecular order with the alkyl chains tightly packed like crystal in the LB films deposited at the zero and higher surface pressures. These experimental results indicate that, in the Langmuir film as the precursor of LB films, stearic acid molecules self-aggregate to form two-dimensional crystalline domains already even at the zero surface pressure, which results in the inhomogeneity of monolayer. The analysis of dependence of nu(C=O) intensity on the surface pressure, surface density, and subphase temperature leads to the conclusion that the defects in LB films originate from the Langmuir film and be conserved upon deposition. Annealing below 50 degrees C and cooling could improve the monolayer homogeneity, and thus a defect-free or low-defect LB films can be deposited. Furthermore, ion exchange conducted in the LB films, on the other hand, confirms the existence of structure defects in LB films of stearic acid. The polar plane microstructure, lateral transport along the polar planes and the coordination types of stearic acid/cation system may be the rate-limiting process. The results have implication on the possible uses of stearic acid LB films as ion-exchange materials or sensors. Copyright 2001 Academic Press.     

雷公藤的药效及毒性与微量元素的研究

雷公藤是一种药效大、毒性也大的中药。研究了雷公藤的28种无机元素，发现其有益元素铁、锰、锌、硒含量较高．其有害元素铅、砷、镉含量也较高，与其药效和毒性一一相对应。雷公藤对风湿性关节炎、肾病、肝脏病、皮肤病的疗效．与铁、锰、锌、硒在人体中生物学机理一致。雷公藤对消比道、心血管、肝脏、泌尿系统、造血系统的毒害作用，与铅、砷、镉在人体中的生物学效应一致。所以在使用雷公藤时，应考虑到微量元素作用．可提高雷公藤的疗效，降低其毒性。     

正丁基锂四氢呋喃引发α-甲基苯乙烯阴离子平衡聚合动力学及反应机理研究

本文研究了以正丁基锂为引发剂,四氢呋喃为添加剂,环己烷为溶剂中的α-甲基苯乙烯阴离子平衡聚合动力学。讨论了体系中的反应活性种;提出了聚合机理;得到了聚合温度为20℃时的平衡单体浓度与活性种速率常数及添加剂浓度之间的关系式。     

白血病骨髓移植病人全血微量元素铜的变化及其意义

为了研究白血病骨髓移植病人全血微量元素铜的变化及其意义 ,用原子吸收光谱法检测了正常对照组与白血病骨髓移植患者预处理前及移植后骨髓空虚期全血微量元素铜的含量。结果表明 ,正常对照组全血铜浓度与白血病骨髓移植患者预处理前全血铜浓度差异无显著性 (P >0 0 5 ) ,而与骨髓空虚期全血铜浓度有显著性差异 (P <0 0 5 ) ,说明白血病缓解后血铜接近正常对照组水平 ,而白血病骨髓移植患者预处理后骨髓空虚期全血铜含量高于正常对照组 ,说明预处理影响微量元素铜的代谢 ,本文就其影响机理进行了研究