Production of High-Transverse-Momentum Deuterons and Tritons at an Angle of 40 $${{}^{\circ}}$$ in Proton–Nucleus Interactions at a Beam Energy of 50 GeV

Physics of Atomic Nuclei - Data on the production of positively charged particles emitted at an angle of 40 $${}^{\circ}$$ (in the laboratory frame) with transverse momenta of up to 2.7 GeV $$/c$$...     

Transferrin immunoextraction for determination of carbohydrate‐deficient transferrin in human serum by capillary zone electrophoresis

CZE‐based assays for carbohydrate‐deficient transferrin (CDT) in which serum is mixed with an Fe(III) ion‐containing solution prior to analysis are effective approaches for the determination of CDT in patient samples. Sera of patients with progressed diseases, however, are prone to interferences comigrating with transferrin (Tf) that prevent the proper determination of CDT by CZE in these samples. The need of a simple and economic approach to immunoextract Tf from human serum prompted us to investigate the use of a laboratory‐made anti‐Tf spin column containing polyclonal rabbit anti‐human Tf antibodies linked to Sepharose 4 Fast Flow beads. This article reports extraction column manufacturing and column characterization with sera having normal and elevated CDT levels. The developed procedure was applied to a number of relevant hepatology and dialysis patient samples and could thereby be shown to represent an effective method for extraction and concentration of all Tf isoforms. Furthermore, lipemic sera were delipidated using a mixture of diisopropyl ether and butanol prior to immunoextraction. CDT could unambiguously be determined in all pretreated samples.     

Crop planning optimization model: the validation and verification processes

Each optimization problem in the area of natural resources claims for a specific validation and verification (V&V) procedures which, for overwhelming majority of the models, have not been developed so far. In this paper we develop V&V procedures for the crop planning optimization models in agriculture when the randomness of harvests is considered and complex crop rotation restrictions must hold. We list the criteria for developing V&V processes in this particular case, discuss the restrictions given by the data availability and suggest the V&V procedures. To show its relevance, they are applied to recently constructed stochastic programming model aiming to serve as a decision support tool for crop plan optimization in South Moravian farm. We find that the model is verified and valid and if applied in practice—it thus offers a plausible alternative to standard decision making routine on farms which often leads to breaking the crop rotation rules.     

Study of the Ternary Systems M (II)(NO3)2–LiNO3–H2O ( M (II)?5?Mg, Ca, Sr, Ba) at 25°C

 The isothermal solubility diagrams of four aqueous systems containing lithium nitrate and nitrates of group IIA metals – magnesium, calcium, strontium, and barium – were studied at 25°C. No double salt formation was observed. The results were compared with similar nitrate and chloride systems. Some trends in the shape of the phase diagrams were observed. Hydration analysis was applied to the solubility branches, rendering information about ionic processes in saturated solutions. Further, the ratio of activity coefficients of the saturating solid phase in ternary and binary solutions (γ/γ₀) was obtained.     

Phosphorylated 2-Chloroethynes in the Reactions with Malonic Acid Derivatives: Azirine or Oxazole?

Russian Journal of General Chemistry - The reactions of (2-chloroethynyl)diphenylphosphine oxide with diethyl 2-aminomalonate and of dimethyl (2-chloroethynyl)phosphonate with...     

Bioanalysis of drugs and their metabolites by chiral electromigration techniques (2010–2020)

The further development and application of capillary electromigration techniques for the enantioselective determination of drugs and their metabolites in body fluids, tissues, and in vitro preparations during the 2010 to 2020 time period continued to proof their usefulness and attractiveness in bioanalysis. This review discusses the principles and important aspects of capillary electrophoresis- based chiral drug bioassays, provides a survey of the assays reported during the past 10 years and presents an overview of the key achievements encountered in that time period. For systems with charged chiral selectors, special attention is paid on assays that feature field-amplified sample injection to enable the determination of ppb levels of analytes and optimized online incubation procedures for the rapid assessment of a metabolic pathway. Applications discussed encompass the pharmacokinetics of drug enantiomers in vivo and in vitro, the impact of inhibitors on metabolic steps, the elucidation of the stereoselectivity of drug metabolism in vivo and in vitro, and drug enantiomers in toxicological, forensic, and doping analysis.     

Photoelectric properties ofp-CuInSe2 crystals

Spectra of the photoelectromotive force of p-CuInSe₂ single crystals obtained by directional crystallization of a stoichiometric-composition melt in an upright ampoule have been investigated by the method of phase-sensitive detection. A difference in the phase shifts between the exciting light and the arising photoelectromotive force in the extrinsic (impurity) and intrinsic regions of optical absorption is determined. The lifetime in the region of optical self-absorption is found to equal τ=15·10⁻⁶ at T=77 K. Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 64, No. 1, pp. 129–131, January–February, 1997.     

Finite volume schemes for multi-dimensional hyperbolic systems based on the use of bicharacteristics

In this paper we present recent results for the bicharacteristic based finite volume schemes, the so-called finite volume evolution Galerkin (FVEG) schemes. These methods were proposed to solve multi-dimensional hyperbolic conservation laws. They combine the usually conflicting design objectives of using the conservation form and following the characteristics, or bicharacteristics. This is realized by combining the finite volume formulation with approximate evolution operators, which use bicharacteristics of the multi-dimensional hyperbolic system. In this way all of the infinitely many directions of wave propagation are taken into account. The main goal of this paper is to present a self-contained overview on the recent results. We study the L ¹-stability of the finite volume schemes obtained by various approximations of the flux integrals. Several numerical experiments presented in the last section confirm robustness and correct multi-dimensional behaviour of the FVEG methods. This research has been supported under the VW-Stiftung grant I 76 859, by the grant No 201/03 0570 of the Grant Agency of the Czech Republic, by the Deutsche Forschungsgemeinschaft grant GK 431 and partially by the European network HYKE, funded by the EC as contract HPRN-CT-2002-00282.     

Scenario-based stochastic programs: Resistance with respect to sample

A contamination technique is presented as a numerically tractable tool to post-optimization and analysis of robustness of the optimal value of scenario-based stochastic programs and of the expected value problems. Detailed applications of the method concern the two-stage stochastic linear programs with random recourse and the corresponding robust optimization problems.This work was supported by the Grant Agency of the Czech Republic under Grant No. 402/93/0631.