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近年来中国化学史研究工作的进展 总被引:1,自引:0,他引:1
三联书店于1956年出版拙著《中国化学史论文集》(以下简称《论文集》),其中“我国化学史的研究概况与参考资料”一文,基本上总结了1956年以前中国化学史的研究成果。这篇论文对了解早期的化学史工作,具有一定的参考作用,便于读者简捷地掌握这方面的初步知识。《论文集》中其它文章所引用的材料也只到1956年年初为止。现距《论文集》的编写已经七年多了。七年多来,由于考古学工作者、文物工作者、历史学工作者和化学工作者等的共同努力,我国化学史的研究工作有了很大程度的进展。无论是在实物方 相似文献
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六十年来中国化学史研究概况周嘉华,李劲松(中国科学院自然科学史研究所,北京100010)由化学界前辈任鸿、章鸿钊、王琏等在本世纪20年代开创的我国化学史研究,伴随着近代化学体系在中国的建立,以及现代科学技术的迅猛发展,已经演变成为科学史学科的一个重要... 相似文献
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化学成就的最高奖赏是诺贝尔化学奖。但是,化学史领域也有国际性的奖励,即著名的德克斯特奖(The Dexter Award),这就不是我国化学史工作者尽人皆知的了。德克斯特奖的颁发史,大体上反映了化学史作为一个独立的学术领域在近几十年发展的主流。德克斯特奖的设立情况、获奖成就以及获奖者个人背景资料的统计分析,是化学史研究的重要内容之一,也是我们了解化学史研究的国际学术背景所必不可少的一个方面。 相似文献
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由中国自然辩证法研究会化学化工委员会、中国科学技术史学会化学史专业委员会举办的 2 0 0 0年全国化学哲学与化学史联合年会 2 0 0 0年 1 1月 1 5~ 1 8日在北京大学承泽园召开。来自全国 1 3个省、市、自治区的 50多名代表参加了这次会议 ,共提交论文 70余篇。中国自然辩证法研究会理事长龚育之、副理事长兼秘书长王国政到会讲话 ,并表示祝贺。全国化学哲学与化学史会议自 1 981年召开以来 ,极大地推动了化学哲学与化学史两个学科在中国的快速发展 ,2 0年来培养了大量人才 ,积累了一大批优秀成果。本次会议作为跨世纪年会表现出与以往不… 相似文献
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为了交流近年来化学史研究的成果,讨论并促进高等院校,特别是师范院校的化学史教学,以及确定今后化学史研究的内容和协作,中国科学技术史学会于1982年10月15日至10月20日在四川成都召开了全国第二次化学史学术会议。来自生产、科研、教育和出 相似文献
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Matthias Schiedel Mustafa Moroglu David M. H. Ascough Anna E. R. Chamberlain Jos J. A. G. Kamps Angelina R. Sekirnik Stuart J. Conway 《Angewandte Chemie (International ed. in English)》2019,58(50):17930-17952
Epigenetics is currently the focus of intense research interest across a broad range of disciplines due to its importance in a multitude of biological processes and disease states. Epigenetic functions result partly from modification of the nucleobases in DNA and RNA, and/or post‐translational modifications of histone proteins. These modifications are dynamic, with cellular machinery identified to modulate and interpret the marks. Our focus is on bromodomains, which bind to acetylated lysine residues. Progress in the study of bromodomains, and the development of bromodomain ligands, has been rapid. These advances have been underpinned by many disciplines, but chemistry and chemical biology have undoubtedly played a significant role. Herein, we review the key chemistry and chemical biology approaches that have furthered our study of bromodomains, enabled the development of bromodomain ligands, and played a critical role in the validation of bromodomains as therapeutic targets. 相似文献
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For many years Chemical Abstracts has included in its coverage publications on chemical documentation or chemical information science. Although the bulk of those publications can be found in section 20 of Chemical Abstracts, many relevant articles were found scattered among 39 other sections of CA in 1984-1985. In addition to the scattering of references in CA, the comprehensiveness of Chemical Abstracts as a secondary source for chemical information science is called into question. Data are provided on the journals that contributed the most references on chemical information science and on the languages of publication of relevant articles. 相似文献
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在中学化学影响化学平衡条件的教学中,依据中学化学教材介绍的化学平衡常数表达式,来分析和证明影响化学平衡移动的因素,这是一种新教法。此教法能使学生快速明白和快速判断化学平衡移动的方向。同时,还能使学生进一步理解化学平衡常数的意义。 相似文献
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化学生物学新前沿——化学蛋白质组学 总被引:7,自引:0,他引:7
随着包括人类在内的主要模式生物的基因组计划的完成,生命科学的研究重心转向蛋白质组的研究--在对应基因组的整体蛋白质水平上系统研究调控细胞生命活动的蛋白质.化学蛋白质组学是化学生物学在后基因组时代的最新发展:化学蛋白质组学利用化学小分子为工具和手段,以基于靶蛋白质功能的新战略探测体内蛋白质组,是新一代的功能蛋白质组学.本文综述了化学蛋白质组学的最新进展、有关技术及其在生物医学和药物研发等方面的应用,并对化学蛋白质组学的发展趋势和前景进行了讨论. 相似文献
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大一化学实验课程改革的研究与实践——兼谈《现代化学实验基础》教学体会 总被引:4,自引:0,他引:4
化学是以实验为基础的学科 ,化学实验是全面实施化学教育的最有效的教学形式。我们认为目前的化学实验教学在以下几个方面存在着需要研究和改革的问题。 (1 )实验内容太多 ,且陈旧重复 ,学生学习积极性不高。实验过程基本上是“照方抓药” ,学生独立思考的空间甚少 ,学习效果不理想。 (2 )在化学教育中 ,理论课偏重于知识的形成和发展 ,而实验则是强调其实现过程。化学实验单独设课确实是一大进步 ,但是目前高等院校的化学实验教学仍然是以验证教学内容为目的 ,依附于理论课教学。且过分强调实验课与理论课开设的同步性 ,相继成立的… 相似文献
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Chemical genetics can be defined as the study of biological systems using small molecule tools. Cell permeable and selective small molecules modulate gene product function rapidly, reversibly and can be administered conditionally in either a cellular or organismal context. The small molecule approach provides exacting temporal and quantitative control and is therefore an extremely powerful tool for dissecting biological processes. This tutorial review has been written to introduce the subject to a broad audience and highlights recent developments within the field in four key areas of biology: modulating protein-protein interactions, malaria research, hepatitis C virus research, and disrupting RNA interference pathways. 相似文献
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《Acta Crystallographica. Section C, Structural Chemistry》1983,39(10):1474-1474
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Paxton WF Sundararajan S Mallouk TE Sen A 《Angewandte Chemie (International ed. in English)》2006,45(33):5420-5429
Research into the autonomous motion of artificial nano- and microscale objects provides basic principles to explore possible applications, such as self-assembly of superstructures, roving sensors, and drug delivery. Although the systems described have unique propulsion mechanisms, motility in each case is made possible by the conversion of locally available chemical energy into mechanical energy. The use of catalysts onboard can afford nondissipative systems that are capable of directed motion. Key to the design of nano- and micromotors is the asymmetric placement of the catalyst: its placement in an environment containing a suitable substrate translates into non-uniform consumption of the substrate and distribution of reaction products, which results in the motility of the object. These same principles are exploited in nature to effect autonomous motion. 相似文献
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K. L. Kompa 《Angewandte Chemie (International ed. in English)》1970,9(10):773-780
Chemical lasers are based on the new principle of obtaining energy in the form of coherent radiation from chemical reactions. Since the discovery of the first laser of this type in 1965, laser emission has been investigated in a considerable number of fast gasphase reactions. In physical chemistry such lasers provide a diagnostic tool for the detailed investigation of the energy distribution in elementary reactions. The barrier to technological use has probably also been overcome by the recent continuous operation of a chemical hydrogen fluoride laser. An attempt is made in the present article to trace the development of this still youthful field and to demonstrate the possibilities and limitations of the generation of energy with chemical lasers. 相似文献