物理化学实验教学及实验室信息化管理体系的构建与实践

在"世界一流学科"的建设环境下,结合物理化学实验教学和实验室管理现状,利用云班课平台和二维码技术,从实验教学过程和实验室管理等2个方面构建了物理化学实验信息化管理体系,详细介绍了信息化管理体系的构建思路及实践研究.研究表明,物理化学实验教学和实验室进行信息化管理后,提高了教师的工作效率,提升了实验室的管理质量,激发了学生的学习兴趣,受到师生的普遍欢迎.     

利用微信公众平台加强基础化学实验室管理的探索和实践

新媒体微信公众号具有简单、便捷、精准、可持续、学生乐于接受等特点,已渗透到高校学习、生活的每一个角落,也直接影响着高校实验室的信息化建设与管理。为了提高教学实验室的科学化管理水平,本文提出了利用微信公众号构建基础化学实验室管理系统,介绍了相关的应用与实践,这将使实验室管理和实验教学突破时空的限制,提高实验室利用效率,为实验教学和人才培养提供更高水平的服务。     

GB/T19001质量管理体系用于高校教学实验室管理的初步实践

探索高校教学实验室以GB/T19001-2016《质量管理体系要求》为指导准则,拓宽改进实验室管理工作的新思路及应用实践。以解读标准中质量管理第一原则及9.1.2、10.3条款为例,论述转变管理理念,进一步实践以人为本,促进实验技术和管理相关人员"全员参与"和"全过程参与"意识的培养,逐步提升实验室管理效率和水平,提高学生对实验教学服务的满意度。     

美国物理化学的奠基人:亚瑟·阿莫斯·诺伊斯

亚瑟·阿莫斯·诺伊斯（1866—1936）,美国物理化学家、教育家。他在麻省理工学院创立了物理化学研究实验室,并亲自管理实验室17年,该实验室成为美国物理化学家的摇篮。他成为美国化学发展史中的重要人物。他是加州理工学院的缔造者之一,奠定了学院的教育理念并构建了核心课程体系。介绍了亚瑟·阿莫斯·诺伊斯的生平和成就。     

化学生物学专业实验室线上服务平台建设

化学生物学专业实验室线上服务平台,是借助现代化信息技术,以微信公众平台和微信群为载体而创建的一个以学生为本、以实验教学为中心的多元化创新服务平台。平台包括“警钟长鸣”“实验教学”和“平台管理”三大模块,集安全教育、辅助教学和助力实验室高质量管理等多重功能。平台的建设顺应了实验室信息化建设的潮流,也契合了教育教学改革的发展需要,对实验教学的开展具有重要意义。     

关于引进国外大学化学实验教学资源问题的思考

在化学教学改革的新时期,除了要引进实验教科书和虚拟化学实验的教学技术之外,还应该注重学习和研究国外大学的化学实验教学体系、教科书编纂方法以及实验教学和管理人才的培养方法,了解国外化学教学实验室的管理方法和实验室文化.     

基于多元共治视角下的高校实验室安全管理体系建设探索与构建

基于多元共治方法论,以我国高校实验室为研究对象,探讨了当前高校实验室安全管理现状,分析了其存在的问题和缺陷,在传统模式基础上从高校实验室安全组织架构体系、责任层级体系、安全制度体系、安全保障体系、安全培训与宣传体系、风险防控体系、应急处理流程体系、第三方介入服务体系8个方面,构建了新型8LS多元共治高校实验室安全管理体系及其模型图,旨在完善其理论体系研究,以期对我国高校实验室安全管理体系的建设和发展提供新思路。     

物理化学理论与实验教学内容更新与教学模式改革——物理化学教学研究会第五次会议纪要

物理化学教学研究会第五次会议以物理化学及物理化学实验"金课"建设的思路与举措为主题,围绕物理化学教学内容更新、物理化学课程思政建设和学科思维教育、物理化学实验创新设计三个方面展开研讨。相关讨论对今后物理化学课程和实验教学内容更新和教学模式改革具有一定的指导意义。     

基于云班课的物理化学开放性实验教学实践*

以云班课为教学平台,采用翻转课堂为主的教学模式开展物理化学开放性实验教学,详细介绍了开放性实验分层教学体系、实验教学内容、微课的设计方法和实践过程。实践结果表明,通过这些教学手段,教师能顺利地开展开放性实验教学,提升学生的学习兴趣和创新能力,同时也提高了实验室资源的利用率。     

物理化学教学研究会第三次会议纪要

物理化学教学研究会第三次会议以物理化学实验教学改革与建设为主题,介绍了教指委制订的实验教学建议内容,并就今后的物理化学实验教学改革进行了交流和研讨。本文介绍了物理化学实验的特点、当前的改革进展及其局限性,总结了部分高校在实验的目标导向设计、教学模式改革、教学理念和方法改革、教学达成度考核设计、实验新原理新方法引入等方面的做法和经验。论述了近期需要开展的重点工作。对今后的物理化学实验教学改革和建设具有一定的指导意义。     

Synthesis and structure of hydroxyisoxazolidines and derivatives of hydroxylamine and alkenals

The reactions of N-substituted hydroxylamines with alkenals serve as a method for the synthesis of the corresponding 2-substituted 3(5)-hydroxyisoxazolidines. The reaction pathway is determined by the nature of the substituent attached to the nitrogen atom. Ring-chain isomerism has been detected in these newly obtained compoundsTranslated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1270–1276, September, 1987.     

Synthesis and characterization of triazenide and triazene complexes of ruthenium and osmium

Triazenide [M(eta2-1,3-ArNNNAr)P4]BPh4 [M = Ru, Os; Ar = Ph, p-tolyl; P = P(OMe)3, P(OEt)3, PPh(OEt)2] complexes were prepared by allowing triflate [M(kappa2-OTf)P4]OTf species to react first with 1,3-ArN=NN(H)Ar triazene and then with an excess of triethylamine. Alternatively, ruthenium triazenide [Ru(eta2-1,3-ArNNNAr)P4]BPh4 derivatives were obtained by reacting hydride [RuH(eta2-H2)P4]+ and RuH(kappa1-OTf)P4 compounds with 1,3-diaryltriazene. The complexes were characterized by spectroscopy and X-ray crystallography of the [Ru(eta2-1,3-PhNNNPh){P(OEt)3}4]BPh4 derivative. Hydride triazene [OsH(eta1-1,3-ArN=NN(H)Ar)P4]BPh4 [P = P(OEt)3, PPh(OEt)2; Ar = Ph, p-tolyl] and [RuH{eta1-1,3-p-tolyl-N=NN(H)-p-tolyl}{PPh(OEt)2}4]BPh4 derivatives were prepared by allowing kappa1-triflate MH(kappa1-OTf)P4 to react with 1,3-diaryltriazene. The [Os(kappa1-OTf){eta1-1,3-PhN=NN(H)Ph}{P(OEt)3}4]BPh4 intermediate was also obtained. Variable-temperature NMR studies were carried out using 15N-labeled triazene complexes prepared from the 1,3-Ph15N=N15N(H)Ph ligand. Osmium dihydrogen [OsH(eta2-H2)P4]BPh4 complexes [P = P(OEt)3, PPh(OEt)2] react with 1,3-ArN=NN(H)Ar triazene to give the hydride-diazene [OsH(ArN=NH)P4]BPh4 derivatives. The X-ray crystal structure determination of the [OsH(PhN=NH){PPh(OEt)2}4]BPh4 complex is reported. A reaction path to explain the formation of the diazene complexes is also reported.     

Investigation of adhesion and mobility of polyurethane and epoxy-rubber glues and adhesives

The values of activation parameters in uncured and cured epoxy resins, rubbers, and blends thereof are investigated. The dependences of activation energy and adhesion strength of epoxy-rubber compositions on rubber content are determined. The correlation of adhesion and activation energy values for polyurethane rubber and epoxy-rubber compositions is shown.     

Mass and NMR spectra of haplophyllidine and perforine and of their derivatives

Conclusions The mass and NMR spectra of haplophyllidine, perforine, and their derivatives have been studied. The influence of the open and cyclic forms of the molecular ion on the nature of the fragmentation has been discussed. The main routes of fragmentation of the compounds considered are due to the presence of substituents at C₈ and C₄.Khimiya Prirodnykh Soedinenii, Vol. 5, No. 4, pp. 273–279, 1969     

Crystal and molecular structure of aroyl- and acetylhydrazones of acet- and benzaldehydes

Aroyl- and acetylhydrazones of acet- (I) and benzaldehydes (IV) and benzoylhydrazones of acet- (II) and benzaldehydes (III) were studied by x-ray structural and quantum-chemical methods in order to establish their structures. Compund (I) was the EEZ structure in the crystal. Calculations and spectral data showed that the EEE form occurs in nonpolar solvents and in the gas phase. According to crystallographic data molecules (I)–(IV) are the E-isomers (relative to the N-N bond) and the hydrazone fragments are planar. Intermolecular N-H...O H-bonds from in the crystals. The data obtained suggest that the majority of acylhydrazones are conformationally rigid on dissolution although exceptions do occur. Apparently the reasons for the difference of acetyl- and benzoylhydrazones in electrocarboxylation reactions are electronic and not steric factors.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 1, pp. 75–81, January, 1991.     

Preparation and characterization of diarylphosphazene and diarylphosphinohydrazide complexes of titanium, tungsten and ruthenium and phosphorylketimido complexes of rhenium

Reaction of the proligand Ph2PN(SiMe3)2 (L1) with WCl6 gives the oligomeric phosphazene complex [WCl4(NPPh2)]n, 1 and subsequent reaction with PMe2Ph or NBu4Cl gives [WCl4(NPPh2)(PMe2Ph)] (2) or [WCl5(NPPh2)][NBu4] (3), respectively. DF calculations on [WCl5(NPPh2)][NBu4] show a W=N double bond (1.756 A) and a P-N bond distance of 1.701 A, which combined with the geometry about the P atom suggests, there is no P-N multiple bonding. Reaction of L1 with [ReOX3(PPh3)2] in MeCN (X = Cl or Br) gives [ReX2(NC(CH3)P(O)Ph2)(MeCN)(PPh3)](X = Cl, 4, X = Br, 5) which contains the new phosphorylketimido ligand. It is bound to the rhenium centre with a virtually linear Re-N-C arrangement (Re-N-C angle = 176.6 degrees, when X = Cl) and there is multiple bonding between Re and N (Re-N = 1.809(7) A when X = Cl). The proligand Ph2PNHNMe2(L2H) reacts with [(C5H5)TiCl3] to give [(C5H5)TiCl2(Me2NNPPh2)] (6). An X-ray crystal structure of the complex shows the ligand (L2) is bound by both nitrogen atoms. Reaction of the proligands Ph2PNHNR2[R2 = Me2 (L2H), -(CH2CH2)2NCH3 (L3H), (CH2CH2)2CH2 (L4H)] with [{RuCl(mu-Cl)(eta6-p-MeC6H4iPr)}2] gave [RuCl2(eta6-p-MeC6H4iPr)L] {L = L2H (7), L3H (8), L4H (9)}. The X-ray crystal structures of 7-9 confirmed that the phosphinohydrazine ligand is neutral and bound via the phosphorus only. Reaction of complexes 7-9 with AgBF4 resulted in chloride ion abstraction and the formation of the cationic species [RuCl(6-p-MeC6H4iPr)(L)]+ BF4- {(L = L2H (10), L3H (11), L4H (12)}. Finally, reaction of complex 6 with [{RuCl(mu-Cl)(eta6-p-MeC6H4iPr)}2] gave the binuclear species [(eta6-p-MeC6H4iPr)Cl2Ru(mu2,eta3-Ph2PNNMe2)TiCl2(C5H5)], 13.     

Ti-V基储氢合金及其氢化物的物相结构与组分优化设计

Ti-V基储氢合金在室温、常压下即可表现出良好的储氢特性,且质量储氢容量明显高于传统AB₅型储氢合金,从而在氢气的精制和回收、运输和储存及热泵等方面有较早的应用。 此外,在混合气体分离、核反应堆中处理氢的同位素、镍氢电池及燃料电池负极材料等方面也得到了广泛的研究与关注。 基于目前Ti-V基储氢合金的研究现状,概述了该类合金的优势、限制性因素(包括成因)及改性手段。 此外,为了进一步理解Ti-V基合金储氢机理、构建合金组分与储氢特性之间的对应关系,本工作重点围绕Ti-V基储氢合金及其氢化物的结构、组分优化设计展开综述,并对其未来研究方向做出展望。     

Glycolate and Thioglycolate Complexes of Rhenium and Their Oxidative Elimination of Ethylene and of Glycol

Selenium dioxide and osmium tetroxide are effective reagents and catalysts for olefin oxidation, although, owing to their toxicity, reservations remain as to their applicability.^[1] We are therefore seeking more easily handled metal oxides that are soluble in organic solvents and that are as effective as osmium tetroxide in carrying out stereospecific cis hydroxylation of olefins. The rhenium(VII ) oxide 1 , which has meanwhile become readily accessible, is a favorable candidate.^[2]