共查询到20条相似文献,搜索用时 271 毫秒
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磁共振成像是根据生物体磁性核(氢核)在磁场中的表现特性成像的高新技术,它诞生后立即被用于医学诊断,在许多疾病的诊治中发挥了不可取代的作用,本文主要介绍磁共振成像影像诊断学的发展历史,及其它蕴含的创新思维历程,给科技工作者将产生有益的启示。 相似文献
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正电子发射断层照相(PET)的特色与应用 总被引:3,自引:0,他引:3
正电子发射断层照相,称为世界上最先进的医学成像设备,采用NaI和BGO晶体作为探测器,将发射正电子的放射性同位素引入所要观察的局部组织或器官,用作示踪剂,用计算机将探测到的一组图形组建成局部或器官的功能图像,PET这一精密成像工具已广泛应用于临床诊断,如心脏疾病,脑部疾病和肿瘤等。 相似文献
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激光聚变内爆实验中,在燃料中掺杂少量比例的中高Z材料,用X光光谱和X光成像测量掺杂元素的发射信息,诊断燃料的温度、密度和压缩形状。用辐射流体力学数值计算和X光成像后处理程序综合分析方法,给出了内爆靶丸优化设计,并讨论示踪材料在X光诊断中的作用。结果表明:在靶丸燃料D2中掺原子分数约1.0%的氩,内爆压缩中子产额下降约15%。由于氩线发射使整个燃料区X光发射强度提高约50倍,X光成像区域增大约30%,有利于实验诊断测量燃料芯部。为了测量燃料区的边界,在CH内壳层涂厚度0.05 μm的硫,分析表明硫Ly-α单能成像大小与流体力学计算的燃料区大小一致,可用于诊断燃料最终压缩界面。数值分析结果得到了神光Ⅱ间接驱动内爆物理相关实验的验证。 相似文献
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光声内窥成像技术具有高分辨、高精准、功能成像等优点,是目前临床新型成像诊断技术研究的热点。然而,光声内窥成像技术受激光器安全能量阈值和光声换能器灵敏度的制约,现有的光声内窥成像技术大多无法兼顾高成像信噪比和小尺寸要求。为了解决光声信号回波能量低、光声图像信噪比差的问题,该文采用一种带有集成前端放大器的小尺寸的光声探头设计方案,其中心频率达到30 MHz,直径小于2.5 mm,通过仿体实验证明其仿体中的成像深度可达6.5 mm,横向成像分辨率可达144.9μm,纵向分辨率为111.1μm,尤其是,成像信噪比相较于对照组的传统光声换能器提高了11.5 dB。该文研究表明,前端集成放大光声探头能有效提高光声成像信噪比,改善成像质量,为提高光声内窥临床诊断精准度提供了新方法。 相似文献
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圆片上缺陷光学诊断设备的几个关键技术 总被引:1,自引:0,他引:1
简述半导体产业为追求投资回报率已经使得诊断设备由简单的工具发展成为检测缺陷、分类缺陷、分析成因、调整工艺的完善的IYM解决方案。讨论了国外诊断设备当前发展趋势。介绍了半导体圆片缺陷现场光学自动诊断设备的组成,给出了圆片诊断设备的一些重要性能指标。重点介绍了缺陷诊断设备从光机扫描成像到形成圆片图(wafermap)所采用的主要方法及其关键技术的几点考虑,包括:缺陷光散射的计算、空间信号滤波器、暗场显微技术和扫描成像技术、空间信息分析及生成圆片图等。 相似文献
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A. Cysewska-Sobusiak G. Wiczyński Z. Krawiecki A. Sowier 《Opto-Electronics Review》2008,16(2):136-146
The subject matter of this paper concerns advanced techniques of imaging used in diagnosis and minimally invasive procedures
applied in non-operable cases of the digestive tract tumour therapy. The role of optical techniques in current medical imaging
is significant. Optical properties of transilluminated or illuminated tissues and organs depend on strong light absorption
and scattering. Numerous issues related to the result interpretation still remain unsolved. Effectiveness and precision can
be especially improved when some combined methods of imaging are used. Videoendoscopy imaging, X-ray imaging, and endoscopic
ultrasound imaging are three complementary methods applied during the interventions described in this work. All interventions
have concerned with the upper part of the digestive tract. Especially, interdisciplinary issues of combined medical imaging
are presented using some examples of a modern approach to imaging of esophagus and biliary stenting. The selected examples
of effects obtained during interventions assisted by combined imaging of the operation site are presented. The operator can
have great control over the appearance of desirable effects as well as undesirable complications in order to work comfortably
and safe. 相似文献
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Fluorescence spectroscopy and imaging have been widely used for in vivo cancer diagnosis and therapy monitoring in preclinical models, as well as clinical translation. Great attempts have been made to develop novel fluorescence techniques and improve on existing ones, which can now be used in conjunction with newly developed fluorescent probes for specific cancer imaging. In this review, a broad overview of fluorescence techniques is provided, including photodynamic diagnosis, laser confocal endomicroscopy and fluorescence lifetime imaging, coupled with endogenous and exogenous fluorophores. In particular, endogenous fluorophores, such as nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FAD), are highlighted as they are linked to cellular metabolism in precancer growth. The use of near‐infrared dyes, such as indocynanine green (ICG), for imaging deep‐tissue regions is also reviewed. In addition, diagnostic algorithms used for tissue classification and cancer detection will be discussed. Lastly, emerging technologies in fluorescence diagnosis will also be included. 相似文献
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现代的各种医学影像术,如射线成像、CT、正电子发射(PET)、磁共振(MR)、超声(US)、荧光(FL)等都各具特色,并成功地应用于多种疾病的诊疗。但每种影像术都不能对生物组织做出完整的描述。由若干个成像技术组成的多模态成像技术,是获得组织更多信息的有效途径。光声(PA)成像是能提供组织的成分和功能信息的新成像技术。它不仅灵敏,可以对较深层的组织进行实时、快速、安全的成像,而且可以利用光声光热造影剂实施非侵入的光热靶向治疗。因此,与光声成像相结合的多模态分子成像是实现精准诊疗的重要技术途径。该文以手持US-PA探头的双模态成像系统,直径为1 mm的血管內窥镜US-PA成像系统,可同时用于术前和术中的US-PA-FL三模态成像系统,以及采用外磁场可操控的磁共振-光声光热分子造影剂、进行MR-PA成像引导的光热治疗技术为例,对多模态光声分子成像系统在医学诊断、手术和光热治疗方面的进展做简单介绍。 相似文献
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准确重建被测目标的颜色信息对实现可靠的植物病虫害诊断具有十分重要的意义。文章提出把多光谱成像技术应用于植物病虫害诊断,所采集的多光谱图像可以从光谱维和图像维反映被测目标的特征信息。在此基础上,实验采用16个窄带滤色片、单色面阵CCD、积分球混合光源照明和标准观测环境建立了能进行适时、无损检测的多光谱成像系统。并利用该设备对Macbeth色卡中8个色卡进行光谱和颜色重建,重建的结果与光谱辐射度计的测量结果进行了比较。通过对光谱匹配角度和CIE标准色差分析,证明这种多光谱成像系统能够准确、稳定地重建出目标的光谱信息和颜色信息。 相似文献
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为了深入研究可行的中高轨成像技术,本文从探测能力角度(用最低发射激光功率表示)深入分析和比较3种主动干涉合成孔径成像技术——傅立叶望远镜(又称为相干场成像或条纹场扫描成像)、成像相关术(又称为强度相关成像)和剪切光束成像。本文利用光电倍增管的信噪比模型和激光作用距离方程,较为细致地分析每种技术在满足单次信噪比(SNR=5)条件下的极限探测能力。通过仿真分析得出:傅立叶望远镜、成像相关术和剪切光束成像所需的最低单光束单脉冲能量分别为11. 4 J、0. 73 MJ和3. 1 MJ。最终得出傅立叶望远镜是上述3种主动成像技术中在目前技术水平下最适合中高轨目标(约36 000 km)高分辨成像的可用技术的结论。 相似文献
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荧光光谱及其成像技术在光活检中的应用 总被引:11,自引:5,他引:6
分析了人体组织自体荧光的主要物质来源和荧光特性,同时总结了国内外常见的第二代新型光敏剂及其临床应用情况。在此基础上,全面比较了各种应用于早期肿瘤光活检的荧光光谱及其成像技术,并重点讨论了这些技术的基本原理和临床应用现状,以及它们今后的发展方向。 相似文献
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Magnetic resonance in the era of molecular imaging of cancer 总被引:1,自引:0,他引:1
Gore JC Manning HC Quarles CC Waddell KW Yankeelov TE 《Magnetic resonance imaging》2011,29(5):587-600
Magnetic resonance imaging (MRI) has played an important role in the diagnosis and management of cancer since it was first developed, but other modalities also continue to advance and provide complementary information on the status of tumors. In the future, there will be a major continuing role for noninvasive imaging in order to obtain information on the location and extent of cancer, as well as assessments of tissue characteristics that can monitor and predict treatment response and guide patient management. Developments are currently being undertaken that aim to provide improved imaging methods for the detection and evaluation of tumors, for identifying important characteristics of tumors such as the expression levels of cell surface receptors that may dictate what types of therapy will be effective and for evaluating their response to treatments. Molecular imaging techniques based mainly on radionuclide imaging can depict numerous, specific, cellular and molecular markers of disease and have unique potential to address important clinical and research challenges. In this review, we consider what continuing and evolving roles will be played by MRI in this era of molecular imaging. We discuss some of the challenges for MRI of detecting imaging agents that report on molecular events, but highlight also the ability of MRI to assess other features such as cell density, blood flow and metabolism which are not specific hallmarks of cancer but which reflect molecular changes. We discuss the future role of MRI in cancer and describe the use of selected quantitative imaging techniques for characterizing tumors that can be translated to clinical applications, particularly in the context of evaluating novel treatments. 相似文献
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Nuclear Magnetic Resonance Imaging (NMR) was performed on two patients whose clinical radiograph and bone scanning suggested spinal osteomyelitis before and after successful antimicrobial therapy. The images obtained suggest that NMR may be more useful in the diagnosis of this condition than other conventional imaging techniques. Hitherto NMR has not been considered particularly useful for the diagnosis of bone disease. This may be true for cortical bone, from which no signal is obtained using the NMR technique, but for medullary bone it appears to be a potentially useful, non-invasive and safe method of diagnosis. 相似文献
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