共查询到17条相似文献,搜索用时 171 毫秒
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壳聚糖是一种新型高分子功能材料,自身具有优良的生物性能.为克服其溶解性较差等缺陷,扩大其应用范围,常采用物理和化学的手段对壳聚糖改性,以改善其物理、化学性能,本文介绍了自2000年以来国内外关于壳聚糖物理和化学改性方面的最新研究进展,阐释了改性途径以及对改性后所得衍生物的相关表征.主要涉及到壳聚糖的烷基化、酰化以及接枝化改性等途径,并列表比较了以上各种手段的改性效果.本文的下篇<壳聚糖改性技术的新进展Ⅱ.交联化、季铵盐化、羧基化改性以及其低聚糖衍生物>将继续介绍基于壳聚糖的其它改性手段的最新进展. 相似文献
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透明质酸及其衍生物作药物载体 总被引:6,自引:0,他引:6
透明质酸(HA)具有良好的生物相容性和生物降解性,是优良的药物载体。但其稳定性差,对强酸、强碱、热、自由基及透明质酸酶敏感,容易发生降解而限制了其应用。本文简要介绍HA的基本特性及应用,重点阐述了HA经不同的化学改性方法如酯化、交联、接枝所得衍生物作药物载体的最新研究进展。化学改性赋予了HA一系列的优良特性,如适当的机械强度、特殊的流变学特性、良好的稳定性、靶向性等,可提高、扩大HA作药物载体的性能和应用范围。最后展望了透明质酸及其衍生物作药物载体的应用前景。 相似文献
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天然高分子材料研究进展 总被引:10,自引:0,他引:10
综述了近年来天然高分子材料的研究进展。主要介绍纤维素、木质素、淀粉、甲壳素、壳聚糖、其它多糖、蛋白质以及天然橡胶等天然高分子通过化学、物理方法以及纳米技术改性制备具有各种功能及生物可降解性环境友好材料的研究状况,并对此类新材料的应用前景进行了展望。 相似文献
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Nishith A. Chudasama Rosy Alphons Sequeira Kinjal Moradiya Kamalesh Prasad 《Molecules (Basel, Switzerland)》2021,26(9)
Among the various natural polymers, polysaccharides are one of the oldest biopolymers present on the Earth. They play a very crucial role in the survival of both animals and plants. Due to the presence of hydroxyl functional groups in most of the polysaccharides, it is easy to prepare their chemical derivatives. Several polysaccharide derivatives are widely used in a number of industrial applications. The polysaccharides such as cellulose, starch, chitosan, etc., have several applications but due to some distinguished characteristic properties, seaweed polysaccharides are preferred in a number of applications. This review covers published literature on the seaweed polysaccharides, their origin, and extraction from seaweeds, application, and chemical modification. Derivatization of the polysaccharides to impart new functionalities by chemical modification such as esterification, amidation, amination, C-N bond formation, sulphation, acetylation, phosphorylation, and graft copolymerization is discussed. The suitability of extraction of seaweed polysaccharides such as agar, carrageenan, and alginate using ionic solvent systems from a sustainability point of view and future prospects for efficient extraction and functionalization of seaweed polysaccharides is also included in this review article. 相似文献
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《Arabian Journal of Chemistry》2014,7(5):741-746
In the current work some modification reactions have been conducted to modify Chitosan with some organic compounds, such as aldehydes and organic acids. On the other hand, different blends of Chitosan with some carbohydrates were prepared to obtain Chitosan derivatives of certain physical and chemical properties. The obtained products have been characterized with the necessary chemical and spectroscopic techniques. The efficiency of the obtained modified materials has been investigated for separation of metal ions and for water uptake. 相似文献
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生物催化剂酶在高分子改性中的应用 总被引:2,自引:0,他引:2
生物催化剂酶用于高分子合成及改性的研究正在成为国外学者的一个新的研究热点,酶催化反应的专一性,高效性,高选择性及反应条件的相对温和性,使酶催化反应在高分子改性领域更具吸引力,为高分子改性开辟了一条更为清洁,更高效的途径。本文综述了近年来酶催化反应在高分子改性方面的研究进展。 相似文献
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Dr. Fa-Jie Chen Dr. Jianmin Gao 《Chemistry (Weinheim an der Bergstrasse, Germany)》2022,28(66):e202201843
Cysteine bioconjugation serves as a powerful tool in biological research and has been widely used for chemical modification of proteins, constructing antibody-drug conjugates, and enabling cell imaging studies. Cysteine conjugation reactions with fast kinetics and exquisite selectivity have been under heavy pursuit as they would allow clean protein modification with just stoichiometric amounts of reagents, which minimizes side reactions, simplifies purification and broadens functional group tolerance. In this concept, we summarize the recent advances in fast cysteine bioconjugation, and discuss the mechanism and chemical principles that underlie the high efficiencies of the newly developed cysteine reactive reagents. 相似文献