共查询到20条相似文献,搜索用时 500 毫秒
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对硝基苯胺和对碘苯乙醚经取代反应制得4’-硝基-(4-乙氧基苯)苯胺(3);3与对氟苯甲醛经取代反应制得含乙氧基的脂溶性中间体4-[(4’-乙氧基苯基)(4″-硝基苯基)氨基]苯甲醛(5);5与4-N,N-二乙基胺基苄基三苯基鏻盐经Witting成烯反应后经Pd/C催化、水合肼还原合成了新化合物4-[4’-(二乙基氨基)苯乙烯基]-N-(4″-乙氧基苯基)-N-(4-氨基苯基)苯胺,其结构经1H NMR,IR,MS和元素分析表征。 相似文献
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将邻羟苯基引入1,2,3-三唑结构中, 设计合成了10个1-(4-取代苯基)-4-苯基-5-取代-1,2,3-三唑类衍生物. 首先, 以对位取代的芳胺为原料, 经重氮化、叠氮化、闭环和缩合反应制得1-(4-取代苯基)-4-苯基-5-水杨醛亚胺-1,2,3-三唑类衍生物(3a~3e), 再用硼氢化钠还原制得1-(4-取代苯基)-4-苯基-5-(2-羟基苄基)氨基-1,2,3-三唑类衍生物(4a~4e). 目标化合物的结构经核磁、IR及元素分析确认. 抑菌活性测试表明, 当质量浓度为0.1 mg/L时, 除化合物3e和4e外, 所有化合物对白色念球菌的抑菌率均达95%以上, 对大肠杆菌的抑菌率达85%以上, 具有强抑菌活性, 表明该类化合物在抗菌药物开发方面有重要应用价值. 相似文献
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合成了6种1-取代-4,5-二(4-氯苯基)咪唑.以对氯苯乙酸和氯苯为原料,经Friedel-Crafts酰基化反应、二氧化锡氧化、与多聚甲醛和乙酸铵环合制备了中间体4,5-二(4-氯苯基)咪唑(5),5再经取代得到3个1-取代-4,5-二-(4-氯苯基)咪唑类化合物6a-c.6a再分别与液体胺经亲核取代反应得到3个1-取代乙酰胺类-4,5-二-(4-氯苯基)咪唑类化合物7a-c.目标化合物结构用核磁共振氢谱和红外光谱进行了表征. 相似文献
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A. A. Avetisyan I. L. Aleksanyan L. P. Ambartsumyan 《Russian Journal of Organic Chemistry》2005,41(5):772-773
Synthesis was performed of 4-(4-ethoxycarbonylphenylamino)- and 4-(2-carboxyphenylamino)-2-methylquinolines by reaction of 2-methyl-4-chloroquinoline with anesthesin and anthranilic acid. In concentrated sulfuric acid 4-(2-carboxyphenylamino)-2-methylquinoline underwent cyclization into 6-hydroxy-7-methylquinolino[3,2-c]quinoline, and the alkaline hydrolysis of 4-(4-ethoxycarbonylphenyl-amino)quinoline afforded 2-methyl-4-(4-carboxyphenylamino)quinoline.__________Translated from Zhurnal Organicheskoi Khimii, Vol. 41, No. 5, 2005, pp. 786–787.Original Russian Text Copyright © 2005 by Avetisyan, Aleksanyan, Ambartsumyan. 相似文献
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Harutyunyan A. A. Israyelyan S. G. Panosyan H. A. Safaryan M. S. Dilanyan S. V. 《Russian Journal of Organic Chemistry》2020,56(9):1588-1594
Russian Journal of Organic Chemistry - 4-(4-Aminophenyl)-2,6-diphenylpyrimidine was synthesized by reaction of (E)-1-(4-aminophenyl)-3-phenylprop-2-en-1-one with benzamidine and was involved in a... 相似文献
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R. C. Arora V. K. Rastogi A. K. Agrawal S. S. Parmar 《Journal of heterocyclic chemistry》1978,15(5):869-871
Some substituted 2-ethyl-3-(4-hydrazinocarbonylphenyl)-4-quinazolones and 2-ethyl-3-(4-hydrazinocarbonylmethylphenyl)-4-quinazolones were synthesized and characterized by their sharp melting points, elemental analyses and spectral data. 相似文献
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通过缓慢挥发溶剂法得到一种不对称吡喃方酸菁染料的单晶,测定了其晶体结构.其晶系为三斜晶系,空间群为P1,a=0.9228(4),b=1.4122(6),c=0.6124(3)nm,α=93.97(4),β=98.14(5),γ=71.05(4),V=0.7470(6)nm3,Z=1.用晶体结构数据解释了此不对称染料的1H-NMR谱. 相似文献
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Kandavelu Palani Ponnuswamy Ambalavanan Mon Nanjappa Gounder Ponnuswamy Velli Raghukumar Vaylakkavoor T Ramakrishnan 《Analytical sciences》2004,20(2):405-406
4-(4'-Diethylaminophenyl)-6-(4-methoxyphenyl)-(2-pyrrolidin-1-yl)-pyridine-3-carbonitrile (DMPPC) was studied by X-ray diffraction methods due to its non-linear optical properties. The pyrrolidine and pyridine rings adopt half-chair and planar conformations, respectively. The molecules in the crystal are stabilized by C-H...O and C-H...N types of intermolecular interactions in addition to van der Waals forces. 相似文献
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4-(4-Aminophenylamino)-2,2,6,6-tetramethylpiperidine was synthesized by alkylation of 4-aminotriacetoneamine with 4-chloronitrobenzene, followed by hydrogenation of the nitro derivative. Its reactions with acrylic, methacrylic, and itaconic acids were carried out. Transformations of the N-substituted amino acids to derivatives of 2-pyrrolidinone and dihydropyrimidinedione were studied.Kaunas Technological University, Kaunas LT-3028. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 629–631, May, 1997. 相似文献
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Antonov D. S. Tikhomirova T. V. Zav’yalov A. V. Shaposhnikov G. P. 《Russian Journal of General Chemistry》2018,88(9):2013-2019
Russian Journal of General Chemistry - 4{(Z)-[4-(Diethylamino)phenyldiazenyl]}phthalonitrile was synthesized by diazotization and azo coupling and used to prepare... 相似文献