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21.
The diffusion of the anti-microbial chlorhexidine digluconate (CHG) has been studied in C. albicans biofilms by time-of-flight secondary-ion mass spectrometry (TOF-SIMS). C. albicans has been shown to become resistant to common anti-microbial agents, including CHG, when growing as a biofilm. Mass transport resistance within biofilms has commonly been suggested as a resistance mechanism, but measurement of transport for most anti-microbial agents in biofilms has proven extremely difficult because of the heterogeneity of the biofilms and the difficulty in detecting these agents within an intact biofilm. In this study, TOF-SIMS has been used to study the transport of CHG and glucose in a frozen hydrated biofilm. The TOF-SIMS images reveal a progression of CHG from the top of the biofilm to its base with time. Images suggest that there are channels within the biofilm and show preferential binding of CHG to cellular components of the biofilm. Additionally, both living and dead cells can be identified in the TOF-SIMS images by the sequestration of K+ and the presence of cell markers. This study demonstrates that TOF-SIMS has the unique potential to simultaneously observe the presence of an antimicrobial agent, concentration of nutrients, and the viability of the cell population. 相似文献
22.
关新民 《新疆大学学报(理工版)》2002,19(1):95-99
介绍了采用MATLAB V5.2提供的模糊逻辑工具箱来设计研究电孤纺电极调节系统中的模糊--PD控制器,讨论了在SIMULINK环境下模糊-PD控制器的参数自调速原理、结构、建立模糊控制规则库和模糊推论方法,并给出仿真结果与结论。 相似文献
23.
During the course of our investigation of the electron transfer properties of some redox species through highly hydrophobic
long chain alkanethiol molecules on gold in aqueous and non-aqueous solvents, we obtained some intriguing results such as
unusually low interfacial capacitance, very high values of impedance and film resistance, all of which pointed to the possible
existence of a nanometer size interfacial gap between the hydrophobic monolayer and aqueous electrolyte. We explain this phenomenon
by a model for the alkanethiol monolayer—aqueous electrolyte interface, in which the extremely hydrophobic alkanethiol film
repels water molecules adjacent to it and in the process creates a shield between the monolayer film and water. This effectively
increases the overall thickness of the dielectric layer that is manifested as an abnormally low value of interfacial capacitance.
This behaviour is very much akin to the ‘drying transition’ proposed by Lum, Chandler and Weeks in their theory of length
scale dependent hydrophobicity. For small hydrophobic units consisting of apolar solutes, the water molecules can reorganize
around them without sacrificing their hydrogen bonds. Since for an extended hydrophobic unit, the existence of hydrogen bonded
water structure close to it is geometrically unfavourable, there is a net depletion of water molecules in the vicinity leading
to the possible creation of a hydrophobic interfacial gap. 相似文献
24.
A. Khrennikov 《Annalen der Physik》2003,12(10):575-585
We study the probabilistic consequences of the choice of the basic number field in the quantum formalism. We demonstrate that by choosing a number field for a linear space representation of quantum model it is possible to describe various interference phenomena. We analyse interference of probabilistic alternatives induced by real, complex, hyperbolic (Clifford) and p‐adic representations. 相似文献
25.
26.
Teresa Regińska 《BIT Numerical Mathematics》2004,44(1):119-133
The paper concerns conditioning aspects of finite-dimensional problems arising when the Tikhonov regularization is applied
to discrete ill-posed problems. A relation between the regularization parameter and the sensitivity of the regularized solution
is investigated. The main conclusion is that the condition number can be decreased only to the square root of that for the
nonregularized problem. The convergence of solutions of regularized discrete problems to the exact generalized solution is
analyzed just in the case when the regularization corresponds to the minimal condition number. The convergence theorem is
proved under the assumption of the suitable relation between the discretization level and the data error. As an example the
method of truncated singular value decomposition with regularization is considered.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献
27.
Zuo LIU Zhen De WU 《数学学报(英文版)》2005,21(5):997-1000
Let κ be non-negative integer. The unoriented bordism classes, which can be represented as [RP(ξ^κ)] where ξ^κ is a k-plane bundle, form an ideal of the unoriented bordism ring MO.. A group of generators of this ideal expressed by a base of MO. and a necessary and sufficient condition for a bordism class to belong to this ideal are given. 相似文献
28.
系统研究了具有急性和慢性两个阶段的MSIS流行病模型.由两节构成,第1节建立和研究了具有急慢性阶段的MSIS流行病模型;第2节在第1节的基础上建立和研究了具有慢性病病程的MSIS流行病模型.第1节的模型是四个常微分方程构成的方程组.第2节的模型既含有常微分方程,又含有偏微分方程.运用微分方程和积分方程中的理论和方法,得到了这两个模型再生数R0的表达式.证明了当R0<1时,无病平衡态是全局渐近稳定性,给出了各模型地方病平衡态的存在性和稳定性条件. 相似文献
29.
Xuding Zhu 《Journal of Graph Theory》2005,48(3):186-209
For 1 ≤ d ≤ k, let Kk/d be the graph with vertices 0, 1, …, k ? 1, in which i ~j if d ≤ |i ? j| ≤ k ? d. The circular chromatic number χc(G) of a graph G is the minimum of those k/d for which G admits a homomorphism to Kk/d. The circular clique number ωc(G) of G is the maximum of those k/d for which Kk/d admits a homomorphism to G. A graph G is circular perfect if for every induced subgraph H of G, we have χc(H) = ωc(H). In this paper, we prove that if G is circular perfect then for every vertex x of G, NG[x] is a perfect graph. Conversely, we prove that if for every vertex x of G, NG[x] is a perfect graph and G ? N[x] is a bipartite graph with no induced P5 (the path with five vertices), then G is a circular perfect graph. In a companion paper, we apply the main result of this paper to prove an analog of Haj?os theorem for circular chromatic number for k/d ≥ 3. Namely, we shall design a few graph operations and prove that for any k/d ≥ 3, starting from the graph Kk/d, one can construct all graphs of circular chromatic number at least k/d by repeatedly applying these graph operations. © 2005 Wiley Periodicals, Inc. J Graph Theory 48: 186–209, 2005 相似文献
30.
风力发电机组变速恒频控制系统研究 总被引:2,自引:0,他引:2
全面介绍了一种最新应用于风力发电中的新型电机—无刷双馈电机,并分析了这种新型电机作变速恒频运行的原理并对这种电机进行了动态特性仿真研究,给出了形式简洁的控制方程和易于实现的控制方案。 相似文献