| Design and Synthesis of 6 α-Corticosteroid Haptens and Their Bovine Serum Albumin(BSA) Conjugates |
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| 引用本文： | Pi SUN Norihiro KOBAYASHI 等.Design and Synthesis of 6 α-Corticosteroid Haptens and Their Bovine Serum Albumin(BSA) Conjugates[J].中国化学快报,2003,14(3):259-262. |
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| 作者姓名： | Pi SUN Norihiro KOBAYASHI |
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| 作者单位： | GraduateSchoolofPharmaceuricalSciences,TohokuUniversity,Aobayama,Aoba-ku,Sendai980-8578,Japan |
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| 基金项目： | Fanicial support from the Grand-in-aid from Ministry of Education Sports Science and Culture of Japan is greatly acknowledged. |
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| 摘 要： | The site of attachment of protein carrier to corticosteroids has great influence on the specificity of produced antibody.In order to obtain highly specific and accurate antibodies for bioimmunoassay determination of cortisol,different tether lengths of 60633－corticosteroid haptens and their BSA conjugates were designed and synthesized.
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| 关 键 词： | 6α-皮质甾半抗原 分子设计 合成 免疫分析 单克隆抗体 牛血清蛋白 |
Design and Synthesis of 6α-Corticosteroid Haptens and Their Bovine Serum Albumin (BSA) Conjugates |
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| Pi SUN,Norihiro KOBAYASHI,Junichi GOTO.Design and Synthesis of 6α-Corticosteroid Haptens and Their Bovine Serum Albumin (BSA) Conjugates[J].Chinese Chemical Letters,2003,14(3):259-262. |
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| Authors: | Pi SUN Norihiro KOBAYASHI Junichi GOTO |
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| Abstract: | The site of attachment of protein carrier to corticosteroids has great influence on the specificity of produced antibody. In order to obtain highly specific and accurate antibodies for bioimmunoassay determination of cortisol, different tether lengths of 6-corticosteroid haptens and their BSA conjugates were designed and synthesized. |
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| Keywords: | Cortisol hapten monocolonal antibody bioimmunoassay |
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