| Enzyme-catalyzed Transesterification of Unusual Substrate:Synthesis of Acyclovir and L-ascorbic Acid (Vitamin C) Vinyl Esters |
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| 作者姓名： | Xing Tao XUE De Shui LUE |
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| 作者单位： | DepartmentofChemistry,ZhejiangUniversity,HangZhou310027 |
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| 摘 要： | The synthesis of acyclovir and L-ascorbic acid with divinyladipate was performed with alkaline protesae from Bacillus subtilis and lipase from Lipozyme (immobilized from Mucor miehei)in different anhydrous organic solvents.Two corresponding derivatives were obtained.
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| 关 键 词： | 维生素C 合成 L-抗坏血酸乙酰基酯 脂肪酶 碱性蛋白酶 酯基转移作用 |
Enzyme-catalyzed Transesterification of Unusual Substrate: Synthesis of Acyclovir and L-ascorbic Acid (Vitamin C) Vinyl Esters |
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| Xing Tao XUE De Shui LUE.Enzyme-catalyzed Transesterification of Unusual Substrate:Synthesis of Acyclovir and L-ascorbic Acid (Vitamin C) Vinyl Esters[J].Chinese Chemical Letters,2003,14(2):163-166. |
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| Authors: | Xing Tao XUE De Shui LU Zhi Chun CHEN QI Wu Ying CAI Xian Fu LIN |
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| Abstract: | The synthesis of acyclovir and L-ascorbic acid with divinyladipate was performed with alkaline protease from Bacillus subtilis and lipase from Lipozyme (immobilized from Mucor miehei) in different anhydrous organic solvents. Two corresponding derivatives were obtained. |
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| Keywords: | Alkaline protease lipase transesterification acyclovir vitamin C vinyl ester |
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