One-step conversion to tertiary amines: InBr3/Et3SiH-mediated reductive deoxygenation of tertiary amides |
| |
| Authors: | Norio Sakai Kohji Fujii Takeo Konakahara |
| |
| Institution: | Department of Pure and Applied Chemistry, Faculty of Science and Technology, Tokyo University of Science (RIKADAI), Noda, Chiba 278-8510, Japan |
| |
| Abstract: | We have developed a simple and practical procedure for a direct reductive conversion from a variety of tertiary amides to the corresponding tertiary amines using an InBr3/Et3SiH reducing system. This reducing system can be applied to the reduction of a secondary amide and provides a more efficient alternative to conventional methods that use aluminum and boron hydrides. |
| |
| Keywords: | Reduction Amide Amine Indium Silane |
| 本文献已被 ScienceDirect 等数据库收录！ |
