| 环肽合成方法的研究进展 |
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| 引用本文： | 唐艳春,田桂玲,叶蕴华.环肽合成方法的研究进展[J].高等学校化学学报,2000,21(7):1056-1063. |
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| 作者姓名： | 唐艳春 田桂玲 叶蕴华 |
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| 作者单位： | 生物有机与分子工程教育部重点实验室, 北京大学化学与分子工程学院, 北京 100871 |
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| 基金项目： | 国家自然科学基金! (批准号 :2 9772 0 0 1)资助 |
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| 摘 要： | 介绍了纯环肽与杂环肽合成的方法、策略及其优缺点,列举了一些常用缩合试剂,探讨了反应溶液浓度、线型肽前体化合物的结构及构象等因素对环化反应的影响.
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| 关 键 词： | 环肽 缩合试剂 环化 |
| 收稿时间： | 1999-10-07 |
Progress in the Study on Synthetic Method of Cyclopeptide |
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| TANG Yan-Chun,TIAN Gui-Ling,YE Yun-Hua.Progress in the Study on Synthetic Method of Cyclopeptide[J].Chemical Research In Chinese Universities,2000,21(7):1056-1063. |
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| Authors: | TANG Yan-Chun TIAN Gui-Ling YE Yun-Hua |
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| Institution: | Key Laboratory of Bioorganic and Molecular Engineering of Education Ministry, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China |
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| Abstract: | The synthetic method and strategy of cyclopeptide were presented, some efficient coupling reagents were introduced, and different influence factors such as the concentration of reaction solution, structure of linear peptide precursor, conformation etc, were discussed. |
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| Keywords: | Cyclopeptide Coupling reagent Cyclization |
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