用线性溶剂化能相关(LSERs)方法评价聚合物包覆钛胶固定相并与相关固定相比较

利用线性溶剂化能相关(LSERs)方法对聚(乙基苯乙烯-二乙烯基苯)包覆钛胶固定相(ES-DVB-TiO₂)的保留行为进行评价,并与聚丁二烯涂覆钛胶固定相(PBD-TiO₂),键合硅胶固定相(ODS)和树脂固定相(PR-1)作了比较,计算出各变最对logk'的百分方差数,发现V₂、Σα₂^H,和Σβ₂^H对logk'有较大的贡献,与聚合物固定相PRP-1近似,因此它们有相似的保留机理,即吸附机理大于分配机理.

Evaluation of Polymer Encapsulated-TiO2 Stationary Phase and Comparison to Related Phases Using Linear Solvation Energy Relationships

The retention behaviors of poly(ethylstyrene-divinylbenzene) encapsulated-TiO₂ (ES-DVB-TiO₂) were studied by means of linear solvation energy relationships (LSERs). On the ES-DVB-TiO₂ stationary phase, 21 kinds of compounds were tested in mobile phase of methanol and water. Good relationships between log k' (ES-DVB-TiO₂) and LSERs parameters are obtained. Besides, we compared the retention characteristics of ES-DVB-TiO₂,PBD-TiO₂,ODS and PRP-1. According to percent variance, retention on ES-DVB-TiO₂ synthesized in our laboratory is dominated by three major factors:the solute size (V₂)、hydrogen bond donor acidity(Σα₂^H)、and the solute hydrogen bond acceptor basicity (Σβ₂^H). The results suggest that ES-DVB-TiO₂ stationary phase exhibits a more adsorption-like retention mechanism under room temperature.