| CdTe纳米晶与蛋白相互作用研究 |
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| 引用本文： | 李军,袁航,赵奎,洪霞,刘艳梅,马岚,白玉白,李铁津.CdTe纳米晶与蛋白相互作用研究[J].高等学校化学学报,2003,24(7):1293-1295. |
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| 作者姓名： | 李军 袁航 赵奎 洪霞 刘艳梅 马岚 白玉白 李铁津 |
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| 作者单位： | 1. 吉林大学化学学院, 长春 130023;
2. 云南大学单克隆抗体工程技术中心, 昆明 650091 |
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| 基金项目： | 国家自然科学基金 (批准号 :2 0 0 730 16 ,6 0 2 710 2 0 )，国家“973”和“86 3”项目资助 |
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| 摘 要： | 当半导体纳米晶的直径小于其电子的玻尔直径时 ,半导体纳米晶对电子具有量子限域效应 ,其发光波长与纳米晶的尺寸相关 .与有机荧光分子相比 ,荧光半导体纳米晶具有以下优点 :(1 )其激发谱在吸收阈值以上几乎是连续的 ,利于多波长激发 ;(2 )高强荧光发射 ,谱峰窄 ,峰形对称 ;(3 )发射波长随着粒径的增大而有规律地红移 ,只需改变粒径即可获得多色发光 ;(4)纳米晶的发光稳定性好 ,不易被光分解和漂白 .因此 ,半导体纳米晶作为新一代荧光生物标记物已有研究1～ 6] .荧光生物标记要求使用水溶性的纳米粒子 ,水相合成半导体纳米晶操作简便、重复…
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| 关 键 词： | CdTe BSA 抗体 静电作用 配位自组装 光致发光 |
| 文章编号： | 0251-0790(2003)07-1293-03 |
| 收稿时间： | 2003-01-23 |
Studies on Interaction Between CdTe Nanocrystals and Proteins |
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| LI Jun ,YUAN Hang ,ZHAO Kui ,HONG Xia ,LIU Yan-Mei ,MA Lan ,BAI Yu-Bai ,LI Tie-Jin.Studies on Interaction Between CdTe Nanocrystals and Proteins[J].Chemical Research In Chinese Universities,2003,24(7):1293-1295. |
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| Authors: | LI Jun YUAN Hang ZHAO Kui HONG Xia LIU Yan-Mei MA Lan BAI Yu-Bai LI Tie-Jin |
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| Institution: | 1. College of Chemistry, Jilin University, Changchun 130023, China;
2. Monoclonal Antibody Technology Center, Yunnan University, Kunming 650091, China |
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| Abstract: | Thiol-capping of CdTe nanocrystals were prepared in aqueous solution. The emission wavelengths of CdTe nanocrystals could be tuned by the refluxing time. Bioinorganic conjugates between CdTe nanocrystals and BSA were formed via electrostatic/coordinate self-assembly. The photoluminescence intensity of the bioinorganic conjugates was improved obviously. BSA could stabilize the CdTe nanocrystals, and the bioinorganic conjugates at room temperature were stable for a long time. We also demonstrated that CdTe nanocrystals could be blocked with BSA and avoid the nonspecific adsorption. |
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| Keywords: | CdTe BSA Antibody Electrostatic function Coordinate self-assembly Photoluminescence |
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