Kinetics of Adsorption of Thymopentin on a Gel-Type Strong Cation-Exchange Resin |
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Authors: | Xin Li Lei Zhang Yonghui Chang Shubao Shen Hanjie Ying Pingkai Ouyang |
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Institution: | (1) College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, 210009 Nanjing, China |
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Abstract: | The ion-exchange kinetics have been determined for adsorption of thymopentin on a gel-type sulfonated styrene–divinylbenzene
resin converted to the ammonium form. Batch equilibrium and kinetic experiments were performed in chloride ion solutions of
different concentration. Equilibrium data revealed isotherms were a good fit to the constant separation factor isotherm. Because
of the high capacity and low cost of the resin its use for uptake of thymopentin was economically feasible. Kinetic data were
compared with the predictions from the Nernst–Planck and Fick models. The intraparticle and effective diffusivity of thymopentin
were obtained from these models. |
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Keywords: | Ion exchange Gel-type resin Cation exchange Thymopentin Kinetics |
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