Double-Network Heparin Dynamic Hydrogels: Dynagels as Anti-bacterial 3D Cell Culture Scaffolds |
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| Authors: | Han Cui Qimeng Wang Ye Zhang Dr Mihail Barboiu Dr Yan Zhang Prof Jinghua Chen |
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| Institution: | 1. Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, 1800 Lihu Avenue, 214122 Wuxi, P. R. China;2. Institut Europeen des Membranes, Adaptive Supramolecular Nanosystems Group, University of Montpellier, ENSCM-CNRS, Place E. Bataillon CC047, 34095 Montpellier, France |
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| Abstract: | Double cross-linked dynamic hydrogels, dynagels, have been prepared through reversible imine bonds and supramolecular interactions, which showed good pH responsiveness, injectability, self-healing property and biocompatibility. With the further encapsulation of heparin, the obtained hydrogels exhibited good anti-bacterial activity and promotion effects for 3D cell culture. |
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| Keywords: | biomaterials biopolymers dynamic hydrogels gels heparin |
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