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免疫分析技术在农药残留分析中的研究进展及在中药中的应用展望
引用本文:赵志高,骆骄阳,付延伟,徐媛媛,王长健,杨世海,杨美华.免疫分析技术在农药残留分析中的研究进展及在中药中的应用展望[J].分析测试学报,2021,40(1):149-158.
作者姓名:赵志高  骆骄阳  付延伟  徐媛媛  王长健  杨世海  杨美华
作者单位:吉林农业大学中药材学院,吉林长春130118;中国医学科学院北京协和医学院药用植物研究所,北京100193;中国医学科学院北京协和医学院药用植物研究所,北京100193;吉林农业大学中药材学院,吉林长春130118
基金项目:国家重点研发计划(2018YFF0214202);中国医学科学院医学与健康科技创新工程(2016-I2M-1-012);国家自然科学基金(81573595);科技部重大新药创制科技重大专项(2018ZX09721004-010)
摘    要:中药材的农药残留问题一直是人们关注的重点,免疫分析技术作为一项特异性强、灵敏度高的快速分析检测技术,在实现中药材农药残留快速筛查方面发挥着重要作用。该文结合近年免疫分析相关研究进展,对不同的免疫分析技术在中药农药残留分析方面的应用、技术优势以及局限性进行总结分析,并对免疫分析技术的发展前景进行了展望,对免疫分析技术在农残分析领域的发展以及保障中药材的安全方面具有指导意义。

关 键 词:免疫分析  中草药  农药残留  免疫传感器

Research Progress on Immunoassay in Pesticide Residue Analysis and Its Application Prospect in Chinese Herbal Medicine
ZHAO Zhi-gao,LUO Jiao-yang,FU Yan-wei,XU Yuan-yuan,WANG Chang-jian,YANG Shi-hai,YANG Mei-hua.Research Progress on Immunoassay in Pesticide Residue Analysis and Its Application Prospect in Chinese Herbal Medicine[J].Journal of Instrumental Analysis,2021,40(1):149-158.
Authors:ZHAO Zhi-gao  LUO Jiao-yang  FU Yan-wei  XU Yuan-yuan  WANG Chang-jian  YANG Shi-hai  YANG Mei-hua
Institution:(College of Traditional Chinese Medicine,Jilin Agricultural University,Changchun 130118,China;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing 100193,China)
Abstract:The issue of pesticide residues in Chinese medicinal materials has always been a focus of attention.As an important rapid analysis technique with strong specificity and high sensitivity,immunoassay plays an important role in the rapid screening of pesticide residues in Chinese herbal medicine.Combined with the relevant research progress on immunoassay in recent years,the application,technical advantages and limitations of different immunoassay techniques in pesticide residue analysis in Chinese herbal medicine are analyzed and summarized in this review,and the prospect for the development of immunoassay technique is also forecasted.This review has an important instructive to the application of immunoassay in pesticide residue analysis and the safety evaluation of traditional Chinese medicines.
Keywords:immunoassay  Chinese herbal medicine  pesticide residues  immunosensor
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