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Facile construction of pyrrolophenanthridone skeleton via a one-pot intramolecular Heck reaction and oxidation
Authors:Wei Cong  Lei ZhaoXiaoming Wu  Jinyi Xu  Hequan Yao
Institution:State Key Laboratory of Natural Medicines (SKLNM) and Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, PR China
Abstract:Construction of pyrrolophenanthridone skeleton via a one-pot Pd-catalyzed intramolecular Heck reaction followed by oxidation has been achieved in moderate to good yields. The reaction mechanism has been proposed.
Keywords:Pyrrolophenanthridone  One-pot  Indole  Intramolecular Heck reaction  Oxidation
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