| 多维高效液相色谱分离模式组合 |
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| 引用本文： | 刘照胜,李永民,蒋生祥,陈立仁.多维高效液相色谱分离模式组合[J].色谱,1997,15(6):490-493. |
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| 作者姓名： | 刘照胜 李永民 蒋生祥 陈立仁 |
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| 作者单位： | 中国科学院兰州化学物理研究所 |
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| 摘 要： | 简述了多维高效液相色谱法的特点及发展简况，重点对分子排阻色谱／反相色谱、离子交换色谱／反相色谱、正相色谱／反相色谱、分子排阻色谱／离子交换色谱、液固色谱／反相色谱、亲合色谱／反相色谱、非手性柱／手性柱等的联用模式及实际应用进行了概括和总结。
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| 关 键 词： | 多维分离 分离模式组合 高效液相色谱法 |
The Combinations of Separation Modes in Multidimensional High Performance Liquid Chromatography(MDHPLC) |
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| Z Liu,Y Li,S Jiang,L Chen.The Combinations of Separation Modes in Multidimensional High Performance Liquid Chromatography(MDHPLC)[J].Chinese Journal of Chromatography,1997,15(6):490-493. |
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| Authors: | Z Liu Y Li S Jiang L Chen |
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| Institution: | Lanzhou Institute of Chemical Physics, the Chinese Academy of Sciences, Lanzhou, 730000. |
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| Abstract: | MDHPLC is a new chromatographic technique, in which fractions from a separation system are selectively transferred to one or more secondary chromatographic systems with different separation mechanism to enhance resolution and sensitivity, or to decrease analysis times. In this review, the principle, characteristics and developments of MDHPLC are discussed. The various possible combinations of separation modes in HPLC such as, size exclusion chromatography/reversed-phase chromatography (SEC/RPC), ion exchange chromatography/reversed-phase chromatography (IEC/RPC), normal bonded phase chromatography/reversed-phase chromatography (NPC/RPC), size exclusion chromatography/ion exchange chromatography (SEC/IEC), liquid-solid chromatography/reversed-phase chromatography (LSC/RPC), affinity chromatography/reversed-phase chromatography (AC/RPC) and achiral column/chiral column] and their applications are systematically reviewed with 63 references. |
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| Keywords: | high performance liquid chromatography multidimensional separation combination of separation modes |
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