| 表面等离子体共振免疫传感器在蛋白质检测中的应用及其研究进展 |
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| 引用本文： | 徐霞,叶尊忠,吴坚,应义斌.表面等离子体共振免疫传感器在蛋白质检测中的应用及其研究进展[J].分析化学,2010,38(7). |
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| 作者姓名： | 徐霞 叶尊忠 吴坚 应义斌 |
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| 作者单位： | 浙江大学生物系统工程与食品科学学院,杭州,310029 |
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| 摘 要： | 表面等离子体共振(SPR)技术是20世纪90年代发展起来的一种新型技术,应用SPR原理可检测生物传感芯片上配位体与分析物之间的相互作用情况,在生命科学、医疗检测、药物筛选、食品检测及环境监测等领域具有广泛的应用需求.SPR技术可与免疫传感器结合,利用抗原抗体的特异性反应可用于各种蛋白质抗原的检测.本文重点总结了SPR免疫传感器在食品及医疗领域蛋白质检测的应用,综述了近年来SPR免疫传感技术在这该领域的研究热点及进展.
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| 关 键 词： | 表面等离子体共振 免疫传感器 光学生物传感器 蛋白质 综述 |
Application and Research Development of Surface Plasmon Resonance-based Immunosensors for Protein Detection |
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| XU Xia,YE Zun-Zhong,WU Jian,YING Yi-Bin.Application and Research Development of Surface Plasmon Resonance-based Immunosensors for Protein Detection[J].Chinese Journal of Analytical Chemistry,2010,38(7). |
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| Authors: | XU Xia YE Zun-Zhong WU Jian YING Yi-Bin |
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| Institution: | XU Xia,YE Zun-Zhong,WU Jian,YING Yi-Bin (College of Biosystems Engineering and Food Science,Zhejiang University,Hangzhou 310029) |
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| Abstract: | Surface plasmon resonance (SPR) technology,which was initially developed as a novel detection strategy in the 1990s,can be applied for monitoring of interaction between ligand and analyte on a sensor chip.Thus it has been largely demanded in the field of life science,medical testing,drug screening,food and environmental monitoring and so on.As well known,the determination of protein concentration is of particular interest.Combination of SPR technology and immunoassay has been used for protein detection,with... |
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| Keywords: | Surface plasmon resonance Immunosensor Optical biosensor Protein Review |
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