Synthesis and Properties of 1,3-Diaryl-5,6-dihydro-8H-imidazo[2,1-c]-1,4-oxazinium Bromides |
| |
| Authors: | A M Demchenko N A Shtil A P Andrushko A N Krasovsky A N Chernega E B Rusanov V V Pirozhenko M O Lozinskii |
| |
| Institution: | (1) T. G. Shevchenko Chernigov Pedagogical University, Chernigov, 14013, Ukraine;(2) Chernigov Technological University, Chernigov, 14027, Ukraine;(3) Ukraine National Academy of Sciences, Institute of Organic Chemistry, Kiev, 02094, Ukraine |
| |
| Abstract: | It has been established that the condensation of 3-(4-methoxyphenylamino)-5,6-dihydro-2H-1,4-oxazine with substituted phenacyl bromides occurs at the exocyclic nitrogen atom with formation of 3-aryl-3-hydroxy-1-(4-methoxyphenyl)-2,5,6,8-tetrahydro-3H-imidazo2,1-c]-1,4-oxazinium bromides. By treatment of the latter with acetic anhydride 3-aryl-1-(4-methoxyphenyl)-5,6-dihydro-8H-imidazo2,1-c]-1,4-oxazinium bromides are formed. The structures of the compounds synthesized were determined via
1H NMR spectroscopy and X-ray diffraction. |
| |
| Keywords: | heterocyclic amidines 3-(4-methoxyphenylimino)-5 6-dihydro-2H-1 4-oxazine substituted phenacyl bromides 3-ethoxy-5 6-dihydro-2H-1 4-oxazine exocyclic nitrogen atom alkylation |
| 本文献已被 SpringerLink 等数据库收录！ |
|
