| 伊诺沙星分子印迹聚合物的制备及分子识别性能研究 |
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| 引用本文： | 连宁,唐江宏,李卫华,贺香红,周全法.伊诺沙星分子印迹聚合物的制备及分子识别性能研究[J].化学研究与应用,2007,19(12):1335-1338. |
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| 作者姓名： | 连宁 唐江宏 李卫华 贺香红 周全法 |
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| 作者单位： | 江苏技术师范学院化学化工学院,江苏省贵金属深加工技术及应用重点建设实验室,江苏,常州,213001 |
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| 基金项目： | 江苏省“青蓝工程”资助项目 |
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| 摘 要： | 以伊诺沙星为印迹分子、甲基丙烯酸为功能单体、季戊四醇三丙烯酸酯为交联剂,合成了对伊诺沙星有较好选择性的印迹聚合物。利用铽敏化荧光,通过静态平衡结合法和Scatchard分析法研究了此印迹聚合物的结合能力和选择性,结果表明印迹聚合物对伊诺沙星有较高的亲和性和选择性。
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| 关 键 词： | 伊诺沙星 分子印迹聚合物 分子识别 |
| 文章编号： | 1004-1656(2007)12-1335-04 |
| 修稿时间： | 2007年5月16日 |
Synthesis and research of molecule recognition capability of enoxacin molecularly imprinted polymer |
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| LIAN Ning,TANG Jiang-hong,LI Wei-hua,HE Xiang-hong,ZHOU Quan-fa.Synthesis and research of molecule recognition capability of enoxacin molecularly imprinted polymer[J].Chemical Research and Application,2007,19(12):1335-1338. |
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| Authors: | LIAN Ning TANG Jiang-hong LI Wei-hua HE Xiang-hong ZHOU Quan-fa |
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| Abstract: | A molecularly imprinted polymer was prepared using enoxacin as the template molecule,methacylic acid as a monomer and pentaerythritol triacylate as a cross-linker.The imprinted polymer obtained was investigated in equilibrium binding experiments to evaluate the molecular recognition and binding characteristics of the enoxacin molecularly imprinted polymer using sensitized fluorescence of terbium.Scatchard analysis showed that the imprinted polymer exhibited much higher affinity for enoxacin among the tested compounds. |
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| Keywords: | enoxacin molecularly imprinted polymer molecule recognition |
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