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| 水介质中三组分一锅合成1-芳基苯并[f]喹啉衍生物 | |
| 引用本文： | 张梅梅,王香善,李庆,姚昌盛,屠树江.水介质中三组分一锅合成1-芳基苯并[f]喹啉衍生物[J].有机化学,2008,28(5):881-884. |
| 作者姓名： | 张梅梅 王香善 李庆 姚昌盛 屠树江 |
| 作者单位： | 1. 徐州师范大学,江苏省药用植物生物技术重点实验室,徐州221116 2. 徐州师范大学,江苏省药用植物生物技术重点实验室,徐州221116;徐州师范大学化学化工学院,徐州221116 3. 徐州师范大学化学化工学院,徐州,221116 |
| 基金项目： | 江苏省高校自然科学基金，徐州师范大学校科研和教改项目 |
| 摘 要： | 以芳醛、2-萘胺和Meldrum酸为原料, 以水为溶剂, 在回流条件下以三乙基苄基氯化铵为催化剂通过三组分一锅反应, 合成了一系列的1-芳基苯并f]喹啉衍生物. 该方法具有反应条件温和、产率较高(79%～87%)、环境友好等优点. 产物的结构通过熔点, IR, 1H NMR和元素分析表征. |
| 关 键 词： | 苯并[f ]喹啉 水 三乙基苄基氯化铵 合成 |
| 收稿时间： | 2007-7-30 |
| 修稿时间： | 2007-10-11 |
Three-Component One-Pot Synthesis of 1-Aryl-4-benzo[f]quinoline Derivatives in Aqueous Media |
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| ZHANG,Mei-Mei,WANG,Xiang-Shan,LI,Qing,YAO,Chang-Sheng,TU,Shu-Jiang.Three-Component One-Pot Synthesis of 1-Aryl-4-benzo[f]quinoline Derivatives in Aqueous Media[J].Chinese Journal of Organic Chemistry,2008,28(5):881-884. | |
| Authors: | ZHANG Mei-Mei WANG Xiang-Shan LI Qing YAO Chang-Sheng TU Shu-Jiang |
| Institution: | ( Key Laboratory of Biotechnology on Medical Plant of Jiangsu Province, Xuzhou Normal Univer-sity, Xuzhou 221116)(School of Chemistry and Chemical Engineering, Xuzhou Normal University, Xuzhou 221116) |
| Abstract: | A series of 1-aryl-1,2-dihydrobenzof]quinolin-3(4H)-one derivatives were synthesized by a three-component one-pot reaction of benzaldehyde, naphthalene-2-amine and meldrum’s acid at refluxing temperature catalyzed by triethylbenzylammonium chloride in water. This method has the advantages of milder reaction conditions, good yields (79%～87%) and environmental benignity. The structures of the products were characterized by melting points, IR, 1H NMR spectra and elemental analysis. |
| Keywords: | benzo[f]quinoline water triethylbenzylammonium chloride synthesis |
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