| Dynamical Analysis of Protein Regulatory Network in Budding Yeast Nucleus |
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| 作者姓名： | 李方廷 贾珣 |
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| 作者单位： | School of Physics and Centre for Theoretical Biology, Peking University, Beijing 100871 |
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| 基金项目： | Supported by the National Key Basic Research Project of China under Grant No 2003CB715900, and the Tai-Zhao Scholarship Fund. |
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| 摘 要： | Recent progresses in the protein regulatory network of budding yeast Saccharomyces cerevisiae have provided a global picture of its protein network for further dynamical research. We simplify and modularize the protein regulatory networks in yeast nucleus, and study the dynamical properties of the core 37-node network by a Boolean network model, especially the evolution steps and final fixed points. Our simulation results show that the number of fixed points N（k） for a given size of the attraction basin k obeys a power-law distribution N（k） χ k^-2.024. The yeast network is more similar to a scale-free network than a random network in the above dynamical properties.
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| 关 键 词： | 动力学分析 蛋白质网络 酵母细胞核 生物物理学 |
| 收稿时间： | 2006-04-06 |
| 修稿时间： | 2006-04-06 |
Dynamical Analysis of Protein Regulatory Network in Budding Yeast Nucleus |
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| LI Fang-Ting,JIA Xun.Dynamical Analysis of Protein Regulatory Network in Budding Yeast Nucleus[J].Chinese Physics Letters,2006,23(8):2307-2310. |
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| Authors: | LI Fang-Ting JIA Xun |
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| Institution: | School of Physics and Centre for Theoretical Biology, Peking University, Beijing 100871 |
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| Abstract: | |
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| Keywords: | 87 10 +e 87 16 Yc 87 16 Aa |
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