| 肿瘤细胞辐射敏感性相关蛋白研究进展 |
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| 引用本文： | 李鸿岩,谢漪,张昕,张红.肿瘤细胞辐射敏感性相关蛋白研究进展[J].原子核物理评论,2012,29(3):300-304. |
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| 作者姓名： | 李鸿岩 谢漪 张昕 张红 |
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| 作者单位： | 1.中国科学院近代物理研究所重离子辐射医学研究室, 甘肃 兰州730000;2.中国科学院重离子束辐射生物医学重点实验室, 甘肃 兰州 730000;3.甘肃省重离子束辐射医学应用基础重点实验室, 甘肃 兰州 730000;4.中国科学院研究生院, 北京100049 |
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| 基金项目： | 国家重点基础研究发展计划项目(973计划)，国家自然科学基金重点项目，甘肃省2007年重大科技专项项目 |
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| 摘 要： | 重点综述了Siah， HIF， NF-κB和DNA-PK蛋白与肿瘤细胞辐射敏感性关系的最新研究进展。 总结了中国科学院重离子束辐射生物医学重点实验室近几年来在BRCA1等肿瘤细胞辐射敏感性相关蛋白方面的研究工作。 简介了HLET C离子束治疗肿瘤的优点。 展望了此实验室借助兰州重离子研究装置(HIRFL)提供的C离子束研究肿瘤细胞辐射敏感性相关蛋白的目标和方向。 The research progress of tumor cells radiosensitivity associated protein Siah, HIF,NF-κB and DNA-PK are summarized and reviewed. The recent works of our laboratory on tumor cells radiosensitivity associated proteins such as BRCA1 are demonstrated. In the present review, we focused on discussions about the advantages of heavy ion therapy and its possible application in the research of radiosensitivity associated proteins. At the end of this review, we highlighted the future trend and potential targets in the study of tumor cells radiosensitivity associated proteins.
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| 关 键 词： | 肿瘤 辐射敏感性 蛋白质 |
| 收稿时间： | 1900-01-01 |
Study of Tumor Cells Radiosensitivity Associated Proteins |
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| LI Hong-yan,XIE Yi,ZHANG Xin,ZHANG Hong.Study of Tumor Cells Radiosensitivity Associated Proteins[J].Nuclear Physics Review,2012,29(3):300-304. |
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| Authors: | LI Hong-yan XIE Yi ZHANG Xin ZHANG Hong |
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| Institution: | 1,2,3(1.Department of Heavy Ion Radiation Medicine,Institute of Modern Physics, Chinese Academy of Sciences,Lanzhou 730000,China; 2.Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences,Lanzhou 730000,China; 3.Key Laboratory of Heavy Ion Radiation Medicine of Gansu Province,Lanzhou 730000,China; 4.Graduate University of China Academy of Sciences,Beijing 100049,China) |
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| Abstract: | The research progress of tumor cells radiosensitivity associated protein Siah,HIF,NF-κB and DNA-PK are summarized and reviewed.The recent works of our laboratory on tumor cells radiosensitivity associated proteins such as BRCA1 are demonstrated.In the present review,we focused on discussions about the advantages of heavy ion therapy and its possible application in the research of radiosensitivity associated proteins.At the end of this review,we highlighted the future trend and potential targets in the study of tumor cells radiosensitivity associated proteins. |
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| Keywords: | radiosensitivity protein |
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