| Ga(OTf)3催化合成苯并二氮杂卓及其结构解析 |
| |
| 引用本文： | 王璐,潘向强,蔡晶晶,邹建平.Ga(OTf)3催化合成苯并二氮杂卓及其结构解析[J].波谱学杂志,2011,28(3):383-389. |
| |
| 作者姓名： | 王璐 潘向强 蔡晶晶 邹建平 |
| |
| 作者单位： | 苏州大学分析测试中心,江苏苏州,215123;苏州大学材料与化学化工学部,江苏省有机合成重点实验室,江苏苏州215123 |
| |
| 基金项目： | 国家自然科学基金资助项目(20772088) |
| |
| 摘 要： | 以邻苯二胺和丙炔酸酯为原料，Ga(OTf)3催化一锅法合成了一类新型的1，5-苯并二氮杂卓衍生物，超声波辅助加快了反应的进行，该反应条件温和，反应时间短. 利用1H NMR、13C NMR 确定了该产物的结构，并通过DEPT、1H-1H COSY、HMQC、HMBC等2D NMR谱，对化合物的1H NMR和13C NMR数据进行了详细的归属，讨论了化合物的质谱裂解规律，进一步确证了该化合物的结构.
|
| 关 键 词： | 核磁共振(NMR) 归属 2D NMR 飞行时间质谱 1 5-苯并二氮杂卓 Ga(OTf)3 |
| 收稿时间： | 2010-12-07 |
Synthesis and Spectroscopic Characterization of a Novel 1,5-Dibenzodiazepine Derivative |
| |
| WANG Lu,PAN Xiang-qiang,CAI Jing-jing,ZOU Jian-ping.Synthesis and Spectroscopic Characterization of a Novel 1,5-Dibenzodiazepine Derivative[J].Chinese Journal of Magnetic Resonance,2011,28(3):383-389. |
| |
| Authors: | WANG Lu PAN Xiang-qiang CAI Jing-jing ZOU Jian-ping |
| |
| Institution: | 1. Testing and Analysis Center, Soochow University, Suzhou 215123, China；;
2. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China |
| |
| Abstract: | Gallium (III) triflate-catalyzed reaction between o-phenylenediamine and ethyl propiolate under solvent-free and ultrasonic irradiation conditions produced a novel 1, 5-benzodiazepine derivative with a yield rate of 88%. Complete assignment of the 1H and 13C NMR chemical shift of the compound was obtained using 2D NMR techniques, including DEPT, 1H-1H COSY, 1H-13C HMQC and 1H-13C HMBC. Mass fragmentation pathway was proposed based on the high resolution MS spectrum of the compound. |
| |
| Keywords: | NMR assignment 2D NMR TOF MS 1 5-benzodiazepine derivative Ga(OTf)3 |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《波谱学杂志》浏览原始摘要信息 |
| 点击此处可从《波谱学杂志》下载免费的PDF全文 |
|
