| 用DCC/DMAP合成N-苄氧羰基氨基酸薄荷酯 |
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| 引用本文： | 李前荣,顾承志,尹浩,张毅.用DCC/DMAP合成N-苄氧羰基氨基酸薄荷酯[J].有机化学,2005,25(11):1416-1419. |
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| 作者姓名： | 李前荣 顾承志 尹浩 张毅 |
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| 作者单位： | 1. 中国科学院中国科技大学结构分析重点实验室,合肥,230026
2. 中国科学院中国科技大学结构分析重点实验室,合肥,230026;石河子大学化学系,石河子,832003 |
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| 摘 要： | 以乙腈为溶剂, 用DCC/DMAP偶合法合成了5个N-苄氧羰基氨基酸薄荷酯, 产率90%～94%. 起始原料氨基酸包括: 甘氨酸, DL-蛋氨酸, β-丙氨酸, L-缬氨酸和L-脯氨酸. 给出了目标产物的氢谱、碳谱、红外光谱、质谱、高分辨质谱和元素分析数据.
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| 关 键 词： | 氨基酸 薄荷醇 酯化 DCC/DMAP 天然产物 |
| 收稿时间： | 12 28 2004 12:00AM |
| 修稿时间： | 06 2 2005 12:00AM |
Synthesis of Menthyl Esters of N-Benzoxycarbonylaminoacid Using DCC/DMAP |
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| LI,Qian-Rong,GU,Cheng-Zhi,YIN,Hao,ZHANG,Yi.Synthesis of Menthyl Esters of N-Benzoxycarbonylaminoacid Using DCC/DMAP[J].Chinese Journal of Organic Chemistry,2005,25(11):1416-1419. |
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| Authors: | LI Qian-Rong GU Cheng-Zhi YIN Hao ZHANG Yi |
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| Institution: | a.Structure Research Laboratory, University of Science and Technology of China, Chinese Academy of Sciences, Hefei 230026;b.Department of Chemistry, Shihezi University, Shihezi 832003 |
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| Abstract: | Five menthyl esters of N-benzoxycarbonylaminoacid were synthesized in 90%～94% yields by using DCC/DMAP coupling method in acetonitrile. The starting material amino acids include glycine, DL-methionine, β-alanine, L-valine and L-proline. The data of 1H NMR, 13C NMR, IR, MS, HRMS spectra and elemental analysis of the target products were reported. |
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| Keywords: | DCC/DMAP |
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