Studies of S-But-3-ynyl and gem-Dimethyl S-But-3-ynyl Thioglycoside Donors in Gold-Catalyzed Glycosylations |
| |
| Authors: | Surya Adhikari Xiaohua Li Jianglong Zhu |
| |
| Institution: | Department of Chemistry and School of Green Chemistry and Engineering , University of Toledo , Toledo , OH , 43606 , USA |
| |
| Abstract: | Gold-catalyzed glycosylation using S-but-3-ynyl and gem-dimethyl S-but-3-ynyl thioglycoside donors has been investigated for the synthesis of various types of complex oligosaccharides. It was found that 2,2-dimethyl S-but-3-ynyl thioglycoside donors are more reactive than their S-but-3-ynyl thioglycoside counterparts and gave the glycoside products in relatively higher yields. |
| |
| Keywords: | Gold Catalysis Alkyne Glycosylation Oligosaccharide synthesis |
|
