| 高空缺氧条件下DPH对脑铁,锌及MDA含量的影响 |
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| 引用本文： | 梅丹,朱志国.高空缺氧条件下DPH对脑铁,锌及MDA含量的影响[J].广东微量元素科学,1997,4(8):17-19. |
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| 作者姓名： | 梅丹 朱志国 |
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| 作者单位： | 空军医学高等专科学校!吉林132013 |
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| 摘 要： | 和原子吸收法测定了高空缺氧条件下ＤＰＨ对大鼠脑组织铁、锌含量的影响，并测定了脑ＭＤＡ含量。结果显示：对照组在高空缺氧条件下，脑组织铁含量明显高于用药组，而脑锌含量明显低于用药组。脑组织ＭＤＡ一明显高于地面对照及用药组，这表明，在高空缺氧条件下，对照组脑组织过氧化反应增强，高于用药组：脑组织ＭＤＡ含量与锌含量成反比。
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| 关 键 词： | 苯妥英钠 高空缺氧 脑组织 丙二醛 铁 锌 |
Effect of DPH on the Content of Fe, Zn and MDA in Brain under High-altitude Condition |
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| Mei Dan, Zhu Zhigou, Dong Hui, Xu Bin, Luo Weiguo, Luo Jun.Effect of DPH on the Content of Fe, Zn and MDA in Brain under High-altitude Condition[J].Trace Elements Science,1997,4(8):17-19. |
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| Authors: | Mei Dan Zhu Zhigou Dong Hui Xu Bin Luo Weiguo Luo Jun |
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| Abstract: | The content of Fe and Zn in brain of rats with or without DPH in 7. 5 km high-altitudedetermined by atondc absorption spectrometry. The content of the brain MDA was also observed. The results showed that the content of brain FE in rat without DPH under hith-alti-tude was much higher than that of normal rat and the content of brain Zn of rat with DPHwas much higher than that of rat without DPH under high-altitude. The content of rat brainMDA without DPH was much higher than that of rat with DPH under high-altitude. The oxgen deficiency makes brain metabolism and hydroperoxidate reaction increased while.DPHmakes brain metabolism and hydroperoxidate reaction decreased. |
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| Keywords: | Dephenylhydantion (DPH) High-altitude Atomic absorption spectrometry |
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