| 基于iPLS的血清胆固醇、甘油三酯近红外定量分析 |
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| 引用本文： | 黄富荣,李仕萍,余健辉,郑仕富,陈哲.基于iPLS的血清胆固醇、甘油三酯近红外定量分析[J].光谱实验室,2011,28(6):2774-2778. |
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| 作者姓名： | 黄富荣 李仕萍 余健辉 郑仕富 陈哲 |
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| 作者单位： | 1. 光电信息与传感技术广东普通高校重点实验室(暨南大学) 广州市黄埔大道西601号510632
2. 暨南大学第一附属医院临床检验中心 广州市黄埔大道西601号510632 |
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| 基金项目： | 国家青年基金(50903038); 广东省科技计划项目(2007B030501008); 广东省自然科学基金(32208005) |
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| 摘 要： | 为了建立血清样品胆固醇、甘油三酯近红外分析最优模型,利用近红外透射光谱技术结合间隔偏最小二乘法（iPLS）建立预测模型。结果表明,胆固醇最优建模波段是1700—1798nm,最优预测模型的相关系数Rp、预测均方差RMSEP分别为0.984、0.198mmol/L;甘油三酯最优建模波段是1654-1746nm,最优预测模型的Rp、RMSEP分别为0.967、0.157mmol/L。采用iPLS建立血清胆固醇、甘油三酯定量分析模型,不仅可以提高模型的预测精度,而且模型更加简洁、数据运算量也更少,优选出的特征谱区还可为设计小型专用近红外分析仪器提供依据。
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| 关 键 词： | 近红外光谱 胆固醇 甘油三酯 间隔偏最小二乘法 波段优选 |
Determination of Cholesterol and Triglyceride in Serum Based on Interval Partial Least Squares by Near-Infrared Spectrum |
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| HUANG Fu-Rong,LI Shi-Ping,YU Jian-Hui,ZHENG Shi-Fu,CHEN Zhe.Determination of Cholesterol and Triglyceride in Serum Based on Interval Partial Least Squares by Near-Infrared Spectrum[J].Chinese Journal of Spectroscopy Laboratory,2011,28(6):2774-2778. |
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| Authors: | HUANG Fu-Rong LI Shi-Ping YU Jian-Hui ZHENG Shi-Fu CHEN Zhe |
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| Institution: | HUANG Fu-Rong LI Shi-Ping YU Jian-Hui ZHENG Shi-Fua CHEN Zhe(Key Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes,Jinan University,Guangzhou 510632,P.R.China)a(Clinical Laboratory Center,the First Affiliated Hospital of Jinan University,P.R.China) |
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| Abstract: | The prediction model was established by near infrared transmission spectrum combined with partial least squares interval（iPLS） to establish the near infrared analytical optimized model for cholesterol and triglyceride in serum.The optimal band for prediction the cholesterol was 1700—1798nm,and the prediction coefficient（Rp）and the root mean square error of prediction（RMSEP） of the optimized prediction model were 0.984 and 0.198mmol/L,respectively,and the optimal band for prediction the triglyceride was 1654—1746nm,and the prediction coefficient（Rp） of 0.967 with the root mean square error of prediction（RMSEP）of 0.157mmol/L.The iPLS model for establishment of analysis model of cholesterol and triglyceride in serum could not only improve precision,but also simplify the model.Optimized wave band selection will provide base for designing minitype special near infrared content analyzer. |
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| Keywords: | Near Infrared Spectrum Cholesterol Triglyceride Interval Partial Least Squares Optimum Wave Band Selection |
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