Detection of V-type nerve agent degradation products at electrodes modified by PPy/PQQ using CaCl2 as supporting electrolyte |
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Authors: | Olga V Shulga Christopher Palmer |
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Institution: | (1) Department of Chemistry, University of Montana, Missoula, MT 59812, USA |
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Abstract: | Electrochemical detection without derivatization was used to detect thiol-containing degradation products of V-type nerve
agents. Electropolymerization of pyrrole was used for entrapment of the biocatalyst PQQ to produce a sensor. Various parameters
which affect the detection processes such as the type of the supporting electrolyte used during electrodeposition and the
thickness of the polypyrrole film were examined and optimized. Electocatalytic oxidation of thiols by the PPy/PQQ electrode
was strongly affected by the presence of Ca2+ cations during electrodeposition of the PPy/PQQ. Cyclic voltammetry, linear sweep voltammetry and amperometry have been used
for electrode characterization. Amperometric detection of the V-type nerve agent thiol degradation products 2-(dimethylamino)ethanethiol
(DMAET) and 2-(diethylamino)ethanethiol (DEAET) was performed at 0.38 V. Linear calibration plots were observed for these
compounds. The detection limits of 4.5 and 3 μM were obtained for DMAET and DEAET respectively, with sensitivities of 1.18
and 1.37 nA μM−1 cm−2. |
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Keywords: | Chemical warfare agents Thiols Pyrroloquinoline quinone Polypyrrole Electrodeposition Amperometry |
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