| 二维DNA晶体的程序化设计与自组装的研究进展 |
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| 引用本文： | 陈亚清,宋琤,肖守军,游效曾.二维DNA晶体的程序化设计与自组装的研究进展[J].无机化学学报,2005,21(10):1443-1449. |
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| 作者姓名： | 陈亚清 宋琤 肖守军 游效曾 |
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| 作者单位： | 配位化学国家重点实验室,南京大学化学化工学院,南京,210093 |
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| 基金项目： | 国家高技术研究发展计划(863计划)资助项目(No.2004AA302G12)。 |
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| 摘 要： | 按照Watson-Crick的碱基配对原则，在理论上能够人工设计与合成DNA碱基序列并自组装成任何一维和二维结构的DNA晶体。DNA分子这种底端向上(bottom-up)的自组装模式为我们提供了一种精确合成纳米材料的方法。本文将从程序化设计、合成刚性的DNA分子瓦(DNA tile)、分子瓦自组装成二维DNA晶体以及二维DNA晶体作为模板在纳米技术中的应用等方面展开，简述这一新奇的并且有着潜在应用前景的研究领域的最新进展。
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| 关 键 词： | 二维DNA晶体 DNA分子瓦 程序化设计 自组装 |
| 文章编号： | 1001-4861(2005)10-1443-07 |
| 收稿时间： | 2005-06-20 |
| 修稿时间： | 2005-09-14 |
The Programmable Design and Self-assembly of Two-Dimensional DNA Crystals |
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| CHEN Ya-Qing,SONG Cheng,XIAO Shou-Jun and YOU Xiao-Zeng.The Programmable Design and Self-assembly of Two-Dimensional DNA Crystals[J].Chinese Journal of Inorganic Chemistry,2005,21(10):1443-1449. |
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| Authors: | CHEN Ya-Qing SONG Cheng XIAO Shou-Jun and YOU Xiao-Zeng |
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| Institution: | State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093,State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093,State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093 and State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093 |
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| Abstract: | Molecular self-assembly presents a bottom-up approach to the fabrication of objects specified with nanometer precision. DNA molecular structures and intermolecular interactions are particularly amenable to design and create complex molecular objects. In this paper, the design of DNA tiles, self-assembly of two dimensional DNA arrays and the recent progress in this prospective field have been briefly reviewed. |
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| Keywords: | 2D DNA crystal DNA tile programmable design self-assembly |
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