| 氧化铝和氧化锆催化剂上2-取代苯并咪唑和1,5-二取代苯并二氮的合成(英文) |
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| 作者姓名： | M. REKHA A. HAMZA B. R. VENUGOPAL N. NAGARAJU |
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| 作者单位： | Catalysis Research Laboratory, St. Joseph’s College and Research Centre, 39 Lalbagh Road, Shanthinagar, Bangalore 560 027, India;Laboratory of Chemistry and Electrochemistry of Surfaces, Facultés Universitaires Notre-Dame de la Paix, Rue de Bruxelles, 61, B-5000, Namur, Belgium |
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| 基金项目： | supported by the UGC, New Delhi |
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| 摘 要： | In this study, alumina, zirconia, manganese oxide/alumina, and manganese oxide/zirconia have been investigated for their catalytic activity in the condensation reaction between o-phenylenediamine and an aldehyde or a ketone to synthesise 2-substituted benzimidazoles and 1,5-disubstituted benzodiazepines respectively. Surface area, surface acidity, and morphology of the catalysts have been analysed and correlated with their catalytic activity. The isolated yields of 2-substituted benzimidazoles and 1,5-disubstituted benzodiazepines are in the range of 30% to 95%. A good correlation between the amount of surface acid sites as well as the surface morphology of the catalysts and the catalytic activity has been observed. This method has been found to be simple and economical. The solid supports could be regenerated and reused without much loss in their activity. Further, the solid supports have been also found to be effective as general catalysts in the condensation of o-phenylenediamine with other substituted aldehydes and ketones.
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| 关 键 词： | 2-substituted benzimidazoles 1 5-disubstituted benzodiazepines manganese oxide alumina zirconia |
Synthesis of 2-Substituted Benzimidazoles and 1,5-Disubstituted Benzodiazepines on Alumina and Zirconia Catalysts |
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| M. REKHA,A. HAMZA,B. R. VENUGOPAL,N. NAGARAJU.Synthesis of 2-Substituted Benzimidazoles and 1,5-Disubstituted Benzodiazepines on Alumina and Zirconia Catalysts[J].Chinese Journal of Catalysis,2012(3):439-446. |
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| Authors: | M REKHA A HAMZA B R VENUGOPAL N NAGARAJU |
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| Institution: | M. REKHA1, A. HAMZA1, B. R. VENUGOPAL2, N. NAGARAJU1,* 1Catalysis Research Laboratory, St. Joseph’s College and Research Centre, 39 Lalbagh Road, Shanthinagar, Bangalore 560 027, India 2Laboratory of Chemistry and Electrochemistry of Surfaces, Facultés Universitaires Notre-Dame de la Paix, Rue de Bruxelles, 61, B-5000, Namur, Belgium |
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| Abstract: | In this study, alumina, zirconia, manganese oxide/alumina, and manganese oxide/zirconia have been investigated for their catalytic activity in the condensation reaction between o-phenylenediamine and an aldehyde or a ketone to synthesise 2-substituted benzimidazoles and 1,5-disubstituted benzodiazepines respectively. Surface area, surface acidity, and morphology of the catalysts have been analysed and correlated with their catalytic activity. The isolated yields of 2-substituted benzimidazoles and 1,5-disubstituted benzodiazepines are in the range of 30% to 95%. A good correlation between the amount of surface acid sites as well as the surface morphology of the catalysts and the catalytic activity has been observed. This method has been found to be simple and economical. The solid supports could be regenerated and reused without much loss in their activity. Further, the solid supports have been also found to be effective as general catalysts in the condensation of o-phenylenediamine with other substituted aldehydes and ketones. |
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| Keywords: | 2-substituted benzimidazoles 1 5-disubstituted benzodiazepines manganese oxide alumina zirconia |
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