仿贻贝粘附蛋白聚合物的研究及动态

贻贝粘附蛋白以其对不同基材表面及在水下都具备高强的粘附能力而闻名。根据仿生学原理,通过将贻贝粘附蛋白功能元即邻苯二酚基团与合成高分子相结合制备仿贻贝粘附蛋白聚合物,达到复制重现甚至超越天然贻贝粘附蛋白粘附效力的目的,是目前贻贝仿生领域研究热点之一。本文综述了近年来国内外仿贻贝粘附蛋白聚合物的研究进展。我们按照主链结构的种类进行了分类,对仿贻贝粘附蛋白聚合物材料的发展过程、材料的设计思路以及应用领域进行了系统的归纳总结。通过研究分子结构与仿生材料功能特性之间的相互关系,希望为以后设计合成新型的功能化的贻贝仿生材料提供有益的借鉴和参考。

An Overview on Study in Mussel Foot-Byssus Protein Mimetic Polymers

Mussel foot-byssus proteins(mfps)are well known for their strong adhesive properties at different substrate surfaces and wet/underwater conditions.By incorporating the functional groups(mainly catechols etc.)in mussel adhesion proteins into synthetic polymers,a new research area called mussel-inspired artificial polymers has become the focus of academic researches,aiming at obtaining similar or even superior adhesive properties compared with the natural one.Here,we have summarized the recent progress in mussel protein-inspired polymers,which are categorized according to the types of main chain structures.By studying the relationship between the molecular structure and the functional properties of biomimetic materials,we hope to provide some helpful reference and guidance for the design and synthesis of new functional mussel-inspired materials.