| Synthesis and Properties of IPN Hydrogels Based on Konjac Glucomannan and Poly（acrylic acid） |
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| 作者姓名： | Bing LIU Zhi Lan LIU Ren Xi ZHUO |
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| 作者单位： | Bing LIU，Zhi Lan LIU，Ren Xi ZHUO Key Laboratory of Biomedical Polymers of Ministry of Education，Department of Chemistry，Wuhan University，Wuhan 430072 |
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| 基金项目： | 国家自然科学基金;国家重点基础研究发展计划(973计划) |
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| 摘 要： | As a random copolymer of β-(1,4) linked D-mannose and D-glucose, konjac gluco- mannan (KGM) is a naturally occurring water-soluble polysaccharide, and has been paid attention in the field of drug controlled release carriers potentially used in colon1,2. …
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| 关 键 词： | 水凝胶 穿插聚合物 PH-灵敏度 葡甘露聚糖 聚丙烯酸 |
| 收稿时间： | 05 15 2006 12:00AM |
Synthesis and Properties of IPN Hydrogels Based on Konjac Glucomannan and Poly(acrylic acid) |
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| Bing LIU Zhi Lan LIU Ren Xi ZHUO.Synthesis and Properties of IPN Hydrogels Based on Konjac Glucomannan and Poly(acrylic acid)[J].Chinese Chemical Letters,2006,17(10):1377-1380. |
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| Authors: | Bing LIU Zhi Lan LIU Ren Xi ZHUO |
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| Abstract: | Novel interpenetrating polymer network (IPN) hydrogels based on konjac glucomannan (KGM) and poly(acrylic acid) (PAA) were prepared by polymerization and cross-linking of acrylic acid (AA) in the pre-fabricated KGM gel. The IPN gel was analyzed by FT-IR. The studies on the equilibrium swelling ratio of IPN hydrogels revealed their sensitive response to environmental pH value. The results of in vitro degradation showed that the IPN hydrogels retain the enzymatic degradation character of KGM. |
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| Keywords: | Hydrogel interpenetrating polymer network pH-sensitivity konjac glucomannan poly(acrylic acid) |
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