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Oxidation of Thiols Using K 2 S 2 O 8 in Ionic Liquid
Authors:Abdol R Hajipour  Majid Mostafavi  Arnold E Ruoho
Institution:1. Department of Pharmacology , University of Wisconsin, Medical School , Madison, Wisconsin, USA;2. Pharmaceutical Research Laboratory, College of Chemistry , Isfahan University of Technology , Isfahan, Iran;3. Pharmaceutical Research Laboratory, College of Chemistry , Isfahan University of Technology , Isfahan, Iran;4. Department of Pharmacology , University of Wisconsin, Medical School , Madison, Wisconsin, USA
Abstract:A green, straightforward, and novel method for oxidation of thiols to the corresponding disulfides is reported using K 2 S 2 O8 in the ionic liquid 1-butyl-3-methylimidazolium bromide (bmim)Br] at 65–70°C. The corresponding disulfides were obtained in excellent yield and short reaction time.
Keywords:Disulfides  ionic liquid  K2S2O8  oxidation  thiols
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