二茂铁亚胺环钯化合物在Heck反应中的催化活性研究

二茂铁亚胺环钯化合物1和2催化Heck反应具有底物范围广、反应条件温和、不需要惰性气体保护、催化活性高、重复使用仍能保持活性的特点。芳基碘化物、溴化物和氯化物都可为反应底物。化合物2应用于碘苯和丙烯酸西酯的反应得到了92%的产率和7360000的转化数；应用于碘苯和丙烯酸乙酯的偶联反应，反复使用五次仍然保持很高的活性。利用高压液相色谱或薄层色谱监测反应。

Studies on the catalytic activity of cyclopalladated ferrocenylimines in heck reaction

A novel kind of ferrocene moieties containing palladacycle catalysts 1 and 2 was synthesized and applied to Heck reaction. It was characterized by a wide variety of substrates, mildness of reaction conditions, freedom from protection of inert gases and high catalytic activity retainable after repeated uses. When catalyst 2 was used to catalyze the coupling ofiodobenzene with butyl acrylate, optimal results were obtained with 7 360 000 turnover number and 92% yield. The catalyst 2 could be reused at least five times in the coupling of iodobenzene with ethyl acrylate. Some of the reactions were followed by HPLC.