Determination of frequently detected herbicides in water by solid-phase microextraction and gas chromatography coupled to ion-trap tandem mass spectrometry |
| |
Authors: | François Perreau Jacques Einhorn |
| |
Institution: | (1) Unité de Phytopharmacie et Médiateurs Chimiques, INRA, Route de Saint-Cyr, 78026 Versailles Cedex, France |
| |
Abstract: | A method based on solid-phase microextraction (SPME) coupled with GC and ion trap tandem mass spectrometry has been developed
for the analysis of nine herbicides and degradation products, among the most frequently found in natural water. A polydimethylsiloxane–divinylbenzene
(PDMS–DVB)-coated fiber was selected to extract the analytes directly from the samples over the 0.01–1 μg L−1 concentration range. Optimization of manual and automated SPME was performed on the basis of desorbed amounts, via various
factorial experiment designs. Of the two modes, the automated one was found to be the most efficient. Memory effect was avoided
owing to the 10-min fiber desorption time. Limits of detection reached down to below 0.01 μg L−1 and repeatability ranged from 3 to 15% in natural water. A validation study was conducted involving the quantitation of the
target compounds in Seine water with SPME/GC–MS-MS external calibration. |
| |
Keywords: | Herbicide Triazine Degradation product Solid-phase microextraction GC– MS-MS analysis Ion trap |
本文献已被 PubMed SpringerLink 等数据库收录! |