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Cooperative Multicomponent Self‐Assembly of Nucleic Acid Structures for the Activation of DNAzyme Cascades: A Paradigm for DNA Sensors and Aptasensors
Authors:Johann Elbaz  Michal Moshe  Bella Shlyahovsky  Itamar Willner Prof
Institution:Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel), Fax: (+972)?2‐652‐7715
Abstract:Self‐assembly line : In the presence of a DNA analyte or low‐molecular‐weight substrates, multicomponent nucleic acids self‐assemble into cooperatively stabilized functional nanostructures (see scheme) that activate DNAzyme cascades.
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Keywords:aptamers  biosensors  DNAzymes  nanostructures  self‐assembly
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