| 蛋白质和变性蛋白质二级结构的FTIR分析进展 |
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| 引用本文： | 何建川,邵阳,张波.蛋白质和变性蛋白质二级结构的FTIR分析进展[J].化学研究与应用,2012(8):1176-1180. |
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| 作者姓名： | 何建川 邵阳 张波 |
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| 作者单位： | 川北医学院基础医学院;川北医学院医学影像研究所 |
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| 基金项目： | 中央财政支持地方高校发展专项资金资助 |
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| 摘 要： | 蛋白质结构的研究一直是人们研究的一个热点,蛋白质在发生变性后,二级结构会改变,从而导致生物活性丧失,这些与医药学及食品科学等领域密切相关。傅里叶变换红外光谱(FTIR)作为一种无损、快速的分析方法在蛋白质二级结构的研究中发挥重要的作用,本文就FTIR对于蛋白质二级结构的研究作一初步概述,主要介绍FTIR研究蛋白质结构的主要方法、红外光谱的谱学特点。
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| 关 键 词： | 蛋白质 二级结构 FTIR 进展 |
Progress in study of protein secondary structure and denaturized protein by FTIR |
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| HE Jian-chuan,SHAO Yang,ZHANG Bo.Progress in study of protein secondary structure and denaturized protein by FTIR[J].Chemical Research and Application,2012(8):1176-1180. |
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| Authors: | HE Jian-chuan SHAO Yang ZHANG Bo |
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| Institution: | 1(1.School of Basic Mecical Sciences of North Sichuan Medical College,Nanchong 637000,China; 2.Medical Imaging Research Institute of North Sichuan Medical College,Nanchong 637000,China) |
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| Abstract: | Study of structure of protein is one of research hotspots.Protein secondary structure will make change with protein denaturation,which leads to losing of bioactivity of protein.Fourier transform infrared spectroscopy(FTIR)has important position in research of structure of protein due to its superiotity.The paper reviews the analytical methods and the spectroscopic features of Study in protein secondary structure and denaturized protein by FTIR. |
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| Keywords: | protein secondary structure FTIR progress |
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