An age-structured within-host HIV model with T-cell competition

Recent studies demonstrate that resource competition is an essential component of T-cell proliferation in HIV progression, which can contribute instructively to the disease development. In this paper, we formulate an age-structured within-host HIV model, in the form of a hyperbolic partial differential equation (PDE) for infected target cells coupled with two ordinary differential equations for uninfected T-cells and the virions, to explore the effects of both the T-cell competition and viral shedding variations on the viral dynamics. The basic reproduction number is derived for a general viral production rate which determines the local stability of the infection-free equilibrium. Two special forms of viral production rates, which are extensively investigated in previous literature, the delayed exponential distribution and a step function rate, are further investigated, where the original system can be reduced into systems of delay differential equations. It is confirmed that there exists a unique positive equilibrium for two special viral production rates when the basic reproduction number is greater than one. However, the model exhibits the phenomenon of backward bifurcation, where two positive steady states coexist with the infection-free equilibrium when the basic reproduction number is less than one.     

DISCUSSION ON TWO PROBLEMS OF THEORETICAL MECHANICS IN COLLEGE MECHANICS COMPETITION1)

针对两道力学竞赛试题,从欧拉动力学方程出发分别给出了更加简化的固连系选取方法,分别命名为"Serret-Andoyer近似固连系"和"虚固连系",在此基础上对第1届全国青年力学竞赛理论力学试题第9题,拓展讨论了大球同步旋转时,小球的稳 定性条件,结果表明后者的稳定临界转速要求更低,这将更有利于提高旋转结构的稳定性;对第12届全国周培源大学生力学 竞赛第3题,剖析了任一纬度的运动规律,发现当体系初始角动量为零时会出现一种简洁又优美的运动模式。     

THE DEVELOPMENT OF NATIONAL ZHOU PEIYUAN COMPETITION ON MECHANICS

全国周培源大学生力学竞赛为《力学与实践》编委会发起并承办的一项大学生科技赛事,经过三十多年的发展,已经成功举办了12届,也成为展示高校力学教学水平的一个窗口。在《力学与实践》创刊40周之际,本文对全国周培源大学生力学竞赛的发展历程和组织模式进行了较为系统的回顾和梳理;对各届的组织规模和创新形式进行归纳与汇总;并通过案例说明力学竞赛对力学教学和人才培养所发挥的作用。     

Bifurcation of Lotka–Volterra competition model with nonlinear boundary conditions

In this paper, we discuss the bifurcation of semi-trivial solutions for the Lotka–Volterra competition model with nonlinear boundary conditions over a smooth bounded domain. Applying the Crandall–Rabinowitz local bifurcation theorem Crandall and Rabinowitz (1971) we prove the existence of a smooth curve bifurcating from the appropriate semi-trivial branch.     

Aggregate production planning for process industries under oligopolistic competition

We consider a competitive version of the traditional aggregate production planning model with capacity constraints. In the general case, multiple products are produced by a few competing producers (oligopoly) with limited capacities. Production quantities, prices and consequently profits depend on production and allocation decisions of each producer. In addition, there is competition for the raw material whose supplies are limited, and where prices reflect these limitations. Such situations have recently occurred in several process industry settings including petro-refining, petrochemicals, basic chemicals, cement, fertilizers, pharmaceuticals, rubber, paper, food processing and metals. We use a successive “Bertrand–Cournot” framework to address this problem and to determine optimal production quantities, prices and profits at the producers and at the raw material supplier. Our analysis allows a new way to understand and evaluate the marginal value of additional capacity when there is competition for the market and raw materials.     

卤代烷反应中取代和消去竞争的教学设计

在卤代烷的取代和消去反应中,进攻试剂均为带负电的实体或多电子基团,因此取代和消去的竞争是卤代烷教学内容的重点和难点。本文介绍我们对这部分教学内容的组织和设计,使学生更好地理解反应底物、进攻试剂和反应条件对优势反应及产物的影响。该教学设计对培养学生的分析能力、思考能力和灵活应用知识的能力具有重要作用。     

对“与封堵溃口有关的重物落水后运动过程的数学建模”的竞赛综述

为了使广大读者熟悉和了解全国研究生数学建模竞赛的相关情况,以2010年B题为例,从命题背景及过程、问题的解答及评审情况和存在的问题等三个方面对该题的整体情况进行介绍.     

Partial extinction,permanence and global attractivity in nonautonomous <Emphasis Type="Italic">n</Emphasis>-species Lotka-Volterra competitive systems with impulses

In this paper, the qualitative properties of general nonautonomous Lotka-Volterra n-species competitive systems with impulsive effects are studied. Some new criteria on the permanence, extinction and global attractivity of partial species are established by used the methods of inequalities estimate and Liapunov functions. As applications, nonautonomous two species Lotka-Volterra systems with impulses are discussed.     

Analysis of industry equilibria in models with sustaining and disruptive technology

This paper analyzes a special type of technology evolution, referred to in the literature as disruptive technology vs. sustaining technology. In general, “old” products based on sustaining technology are perceived to be superior to the “new” ones based on disruptive technology. However, the latter have distinctive features that allow them to attract an exclusive set of customers. Examples include notebooks vs. netbooks, hard-disk drives vs. solid-state drives, laser printers vs. inkjet printers, etc. We consider a model with an established firm and an entrant firm that have heterogeneous product-offering capabilities: the established firm can offer either or both types of products, while the entrant firm can only offer new products. Firms make capacity, pricing, and quantity decisions that maximize their ex-ante profit. Within this framework, we analyze deterministic games with perfect information and stochastic games with uncertain valuation of the disruptive technology. Equilibrium decisions are discussed under various market conditions, as well as under dedicated vs. flexible capacity assumptions.     

具有时滞的非自治Lotka-Volterra竞争系统的持久与灭绝

本文研究具有纯时滞的一般Ｎ－种群非自治Ｌｏｔｋａ－Ｖｏｌｔｅｒｒａ竞争系统的持久性和灭绝性．一些新的判别准则被建立．文献［８－１０］中得到的关于无时滞非自治Ｌｏｔｋａ－Ｖｏｌｔｅｒｒａ竞争系统的结果被改进和推广．