低价钛引起的芳酮肟的反应

在低价钛试剂 (TiCl4/Sm)作用下取代苯乙酮肟发生脱肟反应生成酮 ,而在同样条件下 ,二芳酮肟则生成二芳酮、胺或希夫碱     

A green and efficient deoximation using H_2O_2 catalyzed by montmorillonite-K10 supported CoCl_2

Oximes were oxidized to the corresponding carbonyl compounds in good to high yields by environmentally friendly and green oxidant,H_2O_2 catalyzed by montmorillonite K-10 supported cobalt(Ⅱ) chloride.     

Reductive Deoximation of Aryloximes into Hydrocarbons by Hydrazine/KOH: A Novel Application of the Wolff–Kishner Reduction

We report the reductive deoximation of different substituted aryl, diaryl, and aralkyloximes into the respective methyl or methylene derivatives by hydrazine hydrate/KOH at reflux in satisfactory yields.     

硅胶硫酸催化肟转化为羰基化合物的有效方法

在硅胶硫酸催化和十二烷基磺酸钠存在下,肟与多聚甲醛在90℃的水溶液中搅拌反应15～120 min生成相应的羰基化合物,收率68%～98%.     

Oxidative Cleavage of Oximes with Silica‐Gel‐Supported Chromic Acid in Nonaqueous Media

A simple procedure for a clean and high‐yielding oxidative deoximation of benzaldoximes and ketoximes using a silica‐gel‐supported chromic acid reagent has been developed. This solid‐supported reagent allows us to carry out this reaction in nonaqueous dichloromethane reaction media.     

Direct C-nitration of cyclic α,β-unsaturated oximes under the action of sodium nitrite and acetic acid in methanol

Using a number of cyclic ,-unsaturated oximes of the terpene series and some simplest model compounds as examples, unsaturated oximes bearing a hydrogen atom at the -carbon atom were demonstrated to be converted into -hydroxyiminonitroalkenes under the action of sodium nitrite and acetic acid in methanol. In the case of the introduction of an alkyl substituent at the terminal carbon atom of the diene C=C—C=NOH fragment, the reaction performed under the same conditions gave rise exclusively to conjugated ketone (a deoximation product).     

Ruthenium Trichloride Catalyzed Highly Efficient Deoximation of Oximes to the Carbonyl Compounds and Nitriles without Acceptors

An acceptor‐free catalysis protocol for the deoximation of ketoximes and aldoximes using RuCl₃ as the catalyst has been developed. Under the optimized conditions, various oximes were converted to ketones and nitriles with excellent isolated yields.     

Deoximation Reaction in Room Temperature Ionic Liquids under Mild Conditions

Deoximation in metal chloride ionic liquids based on 1‐alkyl‐3‐methylimidazolium and triethylene ammonium cations, such as AmimBr(Cl)‐MCl_x(A=ethyl, butyl, benzyl; M=Al, Fe, Cu, Sn and Zn; x=2, 3) and Et₃NHCl‐FeCl₃ were investigated under mild conditions. Ferrate chloride ionic liquid was proved to be an effective catalyst for deoximation of cyclohexanone oxime, exhibiting high conversion of oximes and selectivity to cyclohexanone. Good performance for the deoximation of other oximes such as salicylald oxime, acetone oxime, benzophenone oxime, 4‐nitrobenzald oxime, acetophenone oxime, 2‐chlorobenzaldehyde oxime, Acetald oxime, 2‐butanone oxime and (1R)‐camphor oxime was also achieved with bmimBr‐FeCl₃ as catalyst and solvent. The deoximation was determined to carry out via acid‐catalytic hydrolysis and the reaction mechanism was proposed.     

Solvent‐Free Rapid Deprotection of Ketone and Aldehyde Oximes using Periodic Acid

Abstract

Ketone and aldehyde oximes can be readily converted to the corresponding carbonyl compounds in high yields under solvent‐free conditions when treated with periodic acid. Oximes bearing aliphatic C?C bonds can be selectively deoximated. The advantages of this protocol include a rapid reaction rate and a simple workup procedure. No volatile organic solvents are required in the reaction processes.     

An Efficient Solid State Method for Deoximation under Mild Conditions

In recent years, organic reactions conducted in solid state have received increasing attention1 due to short reaction time, mild reaction conditions, excellent selectivity and solvent-free feature. On the other hand, recovery of ketone and aldehyde from o…