A convenient stereoselective synthesis of (R)-(−)-denopamine and (R)-(−)-salmeterol

β-Adrenoreceptor agonists (R)-(−)-denopamine (R)-1 and (R)-(−)-salmeterol (R)-2 have been prepared in good overall yield and high enantioselectivity through a biotransformative pathway.     

Jeans Instability of Self Gravitating Dust Cloud in Presence of Effective Electrostatic Pressure

The role of viscosity coefficient (η'), coulomb coupling parameter (Γ) and dust mass on the growth of jeans mode is investigated in strongly coupled dusty plasma using equations of Generalized Hydrodynamics (GH) Model. The novel aspect of this work is that the force arising due to electrostatic pressure caused by grain grain interaction has been included in the dynamics of dust particles. This force is found to play a significant role in counter balancing the self gravity effect, thereby reducing the growth rate of jeans instability. The present work may provide more physical insight in understanding the mechanisms behind formation of planetesimals, stars etc.     

Jeans Instability of Self Gravitating Dust Cloud in Presence of Effective Electrostatic Pressure

The role of viscosity coefficient(η′), coulomb coupling parameter(Γ) and dust mass on the growth of jeans mode is investigated in strongly coupled dusty plasma using equations of Generalized Hydrodynamics(GH) Model. The novel aspect of this work is that the force arising due to electrostatic pressure caused by grain grain interaction has been included in the dynamics of dust particles. This force is found to play a significant role in counter balancing the self gravity effect, thereby reducing the growth rate of jeans instability. The present work may provide more physical insight in understanding the mechanisms behind formation of planetesimals, stars etc.     

Encapsulation of iron nanoparticles in alginate biopolymer for trichloroethylene remediation

Nanoscale zero-valent iron (NZVI) particles (10–90 nm) were encapsulated in biodegradable calcium-alginate capsules for the first time for application in environmental remediation. Encapsulation is expected to offers distinct advances over entrapment. Trichloroethylene (TCE) degradation was 89–91% in 2 h, and the reaction followed pseudo first order kinetics for encapsulated NZVI systems with an observed reaction rate constant (k _obs) of 1.92–3.23 × 10⁻² min⁻¹ and a surface normalized reaction rate constant (k _sa) of 1.02–1.72 × 10⁻³ L m⁻² min⁻¹. TCE degradation reaction rates for encapsulated and bare NZVI were similar indicating no adverse affects of encapsulation on degradation kinetics. The shelf-life of encapsulated NZVI was found to be four months with little decrease in TCE removal efficiency.     

Synthesis of a novel class of steroidal tetrazolo[1,5-a]pyridines via intramolecular 1,3-dipolar cycloadditions

A facile synthesis of a novel class of steroidal A/B/D-ring annulated tetrazolo[1,5-a]pyridine derivatives has been accomplished via intramolecular 1,3-dipolar cycloaddition reaction of azide with nitrile in aprotic solvent. The synthesis of D-ring annulated tetrazolo[1,5-a]pyridine in alcohol showed incorporation of an alcohol molecule into the heterocyclic system.